Results 211 to 220 of about 2,947,412 (335)

Randomized effectiveness trial of a parent and youth combined intervention on the substance use norms of Latino middle school students

, 2018
Flavio F. Marsiglia, Shiyou Wu, Stephanie L. Ayers, Arianna Weide   +3 more
openalex   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Life-skills training program: its effect on self-efficacy among patients with substance use disorders. [PDF]

BMC Psychol
Abdelmouttelb AA, Elewa SMM, Abdelsalhen FA, Ibrahim FM.   +3 more
europepmc   +1 more source

The effect of changes in society, economy and public health on the disease burden of neurological, mental and substance use disorders: a global longitudinal study [PDF]

, 2019
Yankun Sun, Yao Yao, Yanping Bao, Yan Sun, Le Shi, Jie Shi, Lin Lü   +6 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Prevalence and factors associated with illicit substance use among persons with Schizophrenia at a Tertiary Referral Hospital in Zambia. [PDF]

PLOS Glob Public Health
Kurehwatira KR, Luwaya EL, Povia JP, Siakabanze C, Baines SM, Yumba E, Mulambo P, Masta DN, Ngongo NN, Chishala N, Riwo EO, Mutengo KH, Hatwiko H, Chakulya M, Siame L, Mweene BC, Masenga SK.   +16 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The Community Readiness Instrument: A Quantitative Measurement Using Statistical Best Practices to Assess Systemic Change Readiness. [PDF]

Behav Sci (Basel)
Ricciutti NM, Cureton JL, Zhang S.
europepmc   +1 more source

Childhood sexual abuse and early substance use in adolescent girls: the role of familial influences

, 2013
Carolyn E. Sartor, Mary Waldron, Alexis E. Duncan, Julia D. Grant, Vivia V. McCutcheon, Elliot C. Nelson, Pamela A. F. Madden, Kathleen K. Bucholz, Andrew C. Heath   +8 more
openalex   +1 more source

Mental health and substance use disorders: The reality of youth in custody [PDF]

, 2019
Kim Usher, Lesley Douglas, Debra Jackson
openalex   +1 more source