Results 131 to 140 of about 50,728 (268)

Qualitative analysis of barriers and facilitators to healthcare engagement for people with injecting‐related invasive infections using a social ecological framework

Addiction, EarlyView.
Abstract Background and aims Injecting‐related bacterial infections are increasing in many countries. Systemic infections often require prolonged treatment. Evidence suggests that people who inject drugs who have invasive infections are less likely to complete antimicrobial treatment and have poorer outcomes than patients without a history of injecting
Lucy O. Attwood, Sophia E. Schroeder, Olga Vujovic, Andrew J. Stewardson, Joseph S. Doyle, Paul Dietze, Peter Higgs, Samantha Colledge‐Frisby   +7 more
wiley   +1 more source

HIV pre-exposure prophylaxis programmatic preferences among people who inject drugs: findings from a discrete choice experiment

Addiction Science & Clinical Practice
Background Pre-exposure prophylaxis (PrEP) holds promise for decreasing new HIV infections among people who inject drugs (PWID), yet daily oral PrEP use is low, and PrEP modality and delivery strategy preferences in this population remain understudied ...
William H. Eger, Angela R. Bazzi, Chad J. Valasek, Carlos F. Vera, Alicia Harvey-Vera, Steffanie A. Strathdee, Heather A. Pines   +6 more
doaj   +1 more source

Drug‐Induced Periocular and Ocular Surface Disorders: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Various systemic and topical medications can induce ocular and periocular cutaneous adverse effects (AEs), ranging from mild to severe. These AEs may lead to ocular surface (OS) damage and, in some cases, life‐threatening complications. Drug‐induced ocular adverse reactions are generally classified into two primary categories: toxic reactions ...
Andrea Leonardi, Banu Bozkurt, Diana Silva, Charlotte G. Mortz, Christophe Baudouin, Marina Atanaskovic‐Markovic, Vibha Sharma, Serge Doan, Shweta Agarwal, Daniel Pérez‐Formigo, Maria Joao Vasconcelos, Francoise‐Brignole Baudouin, Gonzalo Chorzepa, Jean‐Luc Fauquert, Virginia Calder, Pascal Demoly, Luis Delgado   +16 more
wiley   +1 more source

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Access to highly active antiretroviral therapy for injection drug users: adherence, resistance, and death

Cadernos de Saúde Pública
Injection drug users (IDUs) continue to comprise a major risk group for HIV infection throughout the world and represent the focal population for HIV epidemics in Asia and Eastern Europe/Russia.
David Vlahov, David D. Celentano
doaj  

Dopamine D3 Receptor Antagonism Reverses the Escalation of Oxycodone Self-administration and Decreases Withdrawal-Induced Hyperalgesia and Irritability-Like Behavior in Oxycodone-Dependent Heterogeneous Stock Rats. [PDF]

, 2019
Prescription opioids, such as oxycodone, are highly effective analgesics for clinical pain management, but approximately 25% of patients who are prescribed opioids misuse them, and 5%-10% develop an opioid use disorder (OUD).
de Guglielmo, Giordano, George, Olivier, Kallupi, Marsida, Newman, Amy H, Sedighim, Sharona   +4 more
core  

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, EarlyView.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source

Syringe exchange programs in Brazil: preliminary assessment of 45 programs

Cadernos de Saúde Pública
The present study aims to evaluate the current operation of Brazilian syringe exchange programs (SEP). After consulting national and regional networks of people working in projects/ programs aiming to reduce drug-related harm, we identified 134 potential
Elize Massard da Fonseca, José Mendes Ribeiro, Neilane Bertoni, Francisco I. Bastos   +3 more
doaj  

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Tetanus in Injecting Drug Users, United Kingdom

Emerging Infectious Diseases, 2006
Susan J.M. Hahné, Joanne M. White, Natasha S. Crowcroft, Moira M. Brett, Robert C. George, Nick J. Beeching, Kirsty Roy, David Goldberg   +7 more
doaj   +1 more source