Results 151 to 160 of about 51,824 (261)

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, EarlyView.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Use of Psychoactive Substances Before Incarceration Among Prison Inmates With Drug Abuse or Dependence: Data From the OPPIDUM Program. [PDF]

Fundam Clin Pharmacol
Abbas Z, Lacroix C, Jouve E, Eiden C, Micallef J, Peyrière H, and the French Addictovigilance network.   +6 more
europepmc   +1 more source

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

Journal of Internal Medicine, EarlyView.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron, Jennifer S. Lin, Mark I. Ryder, Peter Bergman   +3 more
wiley   +1 more source

A Fatal Case Involving Chronic Intravenous Use of Homemade Methcathinone Derived from Pseudoephedrine Tablets: Post-Mortem Concentrations, Health Risk, and Medicolegal Aspect. [PDF]

Int J Mol Sci
Nowak K, Szpot P, Zawadzki M.
europepmc   +1 more source

The Epidemics of Injecting Drug Use and Blood-Borne Disease: A Public Health Perspective [PDF]

, 2011
Gostin, Lawrence O.
core   +2 more sources

Atraumatic acute compartment syndrome secondary to prolonged intoxication induced recumbency: a case series. [PDF]

World J Emerg Med
Greenspan J, Gartenberg A, Sofia Simich C, Halperin M.   +3 more
europepmc   +1 more source

Acute Gluteal Compartment Syndrome and Sciatic Nerve Palsy Following Prolonged Immobilization in an Intravenous Drug User: A Case Report. [PDF]

Am J Case Rep
Papageorgiou P, Giannatos V, Antzoulas P, Argyropoulou E, Koukos C, Kokkalis Z.   +5 more
europepmc   +1 more source

Valproic acid for treatment of traumatic brain injury: Study protocol for the VIBRANT prospective randomized trial

Transfusion, EarlyView.
Abstract Background Traumatic brain injury (TBI) carries significant mortality and morbidity in civilian and military populations. Current treatment guidelines for TBI are primarily supportive, and no pharmacological agent exists to attenuate the progression of brain injury.
Maxime A. Visa, Marjorie R. Liggett, Sharnia Lashley, Umar Bhatti, Zaiba A. Dawood, Alvin Anand, Nathan P. Gill, Denise M. Scholtens, Bowen Wang, Hasan B. Alam   +9 more
wiley   +1 more source

Clavipectoral Fascial Plane Block for a Permanent Pacemaker Insertion in a Claustrophobic Patient With a History of Substance Abuse: A Case Report. [PDF]

Cureus
Sandeep G, Singha SK, Nazir S, Arun TC, Gupta A.   +4 more
europepmc   +1 more source

Surgical impact of laparoscopic and laparotomic elective ovariectomy on inflammatory and oxidative stress biomarkers in anestrus dogs

Veterinary Surgery, EarlyView.
Abstract Objective To compare the systemic inflammatory and oxidative stress responses after elective ovariectomy via open surgery (OPEN) or laparoscopy (LAP) in anestrus bitches. Study design Prospective, blinded, randomized clinical trial. Animals A total of 26 healthy bitches.
Alfonso Calabria, Chiara Del Prete, Maria Pia Pasolini, Veronica Palumbo, Maria Anna Nappo, Silvia Ammirati, Davide Ciccarelli, Fabiana Micieli, Michal Andrzej Kosior, Carmine Carbone, Natascia Cocchia   +10 more
wiley   +1 more source