Results 191 to 200 of about 50,728 (268)

Multidimensional Evaluation of Lisdexamfetamine: Pharmacology, Therapeutic Use, Toxicity and Forensic Implications

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 5, November 2025.
Structure of lisdexamfetamine dimesylate, its active metabolite d‐amphetamine and the essential amino acid l‐lysine, along with the mechanism of action and primary pharmacological and adverse effects associated with lisdexamfetamine dimesylate. TAAR1, trace amine‐associated receptor; VMAT, vesicular monoamine transporter; DAT, dopamine transporter; NAT,
Mariana Silva‐Carvalho, Daniel José Barbosa, Diana Dias da Silva, Ricardo Jorge Dinis‐Oliveira   +3 more
wiley   +1 more source

Drug substitutes - Insights on benefits, risks, detection methods, and management strategies: a systematic review. [PDF]

Front Psychiatry
Bai S, Li M, Tang S, Wan S, Wu R, Chen L, Wang F, Liu S.   +7 more
europepmc   +1 more source

Should self‐administered voluntary assisted dying be supervised? A Queensland case

Medical Journal of Australia, Volume 222, Issue 8, Page 390-393, May 2025.
Eliana Close, Katrine Del Villar, Ben P White   +2 more
wiley   +1 more source

Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential

British Journal of Pharmacology, Volume 182, Issue 21, Page 5090-5118, November 2025.
Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley   +1 more source

A procedure to identify persistent and effort‐independent individual differences in preference for heroin over rewarding social interaction

British Journal of Pharmacology, Volume 182, Issue 22, Page 5596-5610, November 2025.
Background and Purpose In some individuals, opioid use leads to decreased interest in socially relevant rewards. Recent studies showed that after extended‐access heroin self‐administration, rats strongly prefer social interaction over single unit‐dose heroin infusions.
Ginevra D'Ottavio, Alana Sullivan, Sara Pezza, Maria Chiara Ruano, Jacopo Modoni, Ingrid Reverte, Claudia Marchetti, Soami F. Zenoni, Marco Venniro, Michele S. Milella, Fernando Boix, Yavin Shaham, Daniele Caprioli   +12 more
wiley   +1 more source

Synergistic Drug-Induced Diffuse Alveolar Hemorrhage in a Polysubstance User: A Case of Inhaled Cocaine and Fentanyl Toxicity. [PDF]

Cureus
Lopez-Pena BA, Canevaro-Lugo N, Davila-Cardona AU, Ruiz-Ramos M, Perez-Mitchell MC, Fernandez-Gonzalez R.   +5 more
europepmc   +1 more source

Survey on 9 years of anti‐doping controls in horse races in Italy

Equine Veterinary Journal, Volume 57, Issue 6, Page 1592-1599, November 2025.
Abstract Background Doping in racehorses is a threat to horse welfare and the integrity of the sport. Despite its relevance, the literature on the prevalence of anti‐doping violations worldwide is limited. Objectives To analyse anti‐doping violations in racehorses in Italy. Study Design Retrospective observational study.
Mariana Roccaro, Riccardo Rinnovati, Luca Stucchi, Federica La Rocca, Giuseppe Cascio, Angelo Peli   +5 more
wiley   +1 more source

Fatalities in opioid agonist treatment with long-acting injectable buprenorphine. [PDF]

Int J Legal Med
Häkkinen M, Mariottini C, Kriikku P, Ojanperä I.   +3 more
europepmc   +1 more source

Celiac Artery Dissection in an HIV-Positive Patient With Cocaine Use: A Rare Vascular Emergency. [PDF]

Cureus
Rahman H, Merchant A, Patel A, Nagendran A, Lambroussis CG.   +4 more
europepmc   +1 more source

Clinical Management of Synthetic-Cannabinoid-Induced Psychosis: A Systematic Review of Treatment Strategies and Outcomes. [PDF]

Brain Sci
Mosca A, Chiappini S, Miuli A, Cavallotto C, Pettorruso M, Martinotti G, Schifano F.   +6 more
europepmc   +1 more source