Results 131 to 140 of about 2,326,575 (402)
A Departmental Policy Addressing Chemical Substance Abuse [PDF]
John Lecky+7 more
openalex +1 more source
IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu+10 more
wiley +1 more source
Substance Abuse During the Middle School Years: A National Profile [PDF]
John Van Hoose, Stuart M. Cohen
openalex +1 more source
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen+10 more
wiley +1 more source
Objectives: In this study, we aimed to determine the individual characteristics of clients who were referred to residential rehabilitation centers for drug use disorders and to determine their relapse-related factors.
Omid Massah+4 more
doaj
Teen Substance Use and Abuse in the Growing Metro of Des Moines, Iowa [PDF]
uVoice, a youth philanthropy board comprised of twelve students from seven Des Moines-area high schools, spent 2016 identifying unmet needs of central Iowa youth, specifically issues related to substance abuse.Students wrote and released a "White Paper ...
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This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song+24 more
wiley +1 more source
Te Aroha o te Hauangiangi : Māori perspectives on healing from substance abuse : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Māori Studies at Te Pūtahi-ā-Toi School of Māori Studies, Massey University, Palmerston North, Aotearoa/New Zealand [PDF]
This thesis examines and describes Māori cultural components used in the treatment of substance abuse problems in the Taha Māori Programme at Queen Mary Hospital.
Warbrick, Keremete Te Rangimaria
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Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji+12 more
wiley +1 more source
Objectives: This present study aims to examine the effectiveness of cognitive-behavioral-based stress management training on anxiety in female MS patients. Methods: This study employed a semi-experimental research method with pre-test post-test, control
Shafigh Mehraban+3 more
doaj