Results 171 to 180 of about 841,730 (362)
Advanced Science, EarlyView.KPPepGen is a knowledge‐aware prompt diffusion model for the controllable generation of pathogen‐specific AMPs. It outperforms existing methods and is capable of simultaneously generating peptides for distinct pathogens, demonstrating superior performance with favorable properties and docking efficacy.
Yongkang Wang +4 more
wiley +1 more source
Substance abuse by adolescents with criminal behavior
, 1989 A. M. Valeeva, Zh. Zh. Sibgatullin
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Substance Abuse and Schizophrenia: Editors' Introduction [PDF]
, 1997 Thomas R. Kosten, Douglas Ziedonis
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Big Data and AI‐Powered Modeling: A Pathway to Sustainable Precision Animal Nutrition
Advanced Science, EarlyView.This review summarizes the current landscape of big data and AI‐powered modeling in animal nutrition, covering techniques including intelligent data acquisition, data augmentation, explainable machine learning, heuristic algorithms, and life cycle assessment‐based sustainability evaluation.
Shuai Zhang +3 more
wiley +1 more source
Molecular Genetics of Substance Abuse Vulnerability A Current Approach [PDF]
, 1999 George Uhl
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Advanced Science, EarlyView.Physiological flow (0.5 Pa) conditioning promotes resilience of an iPSC‐derived blood–brain barrier endothelium to mild systemic inflammation. In contrast, high “cytokine storm” levels induce barrier breakdown, fibrinogen leakage, and astrocyte activation, reconstituting the two‐hit injury mechanism on‐a‐chip.
Kaihua Chen +15 more
wiley +1 more source
Addressing Trauma in Substance Abuse Treatment with American Indian Adolescents [PDF]
, 1998 Norma Gray
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cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression
Advanced Science, EarlyView.cGAS is a cytosolic DNA sensor known for innate immune defense. cGAS binds and suppresses ALDH2 are showed, limiting acetyl‐CoA production. cGAS loss activates ALDH2, promoting histone acetylation, lipogenesis, and lipid droplets accumulation. cGas‐/‐ mice on a high‐fat diet show signs of worsened MASLD.
Ying Wang +14 more
wiley +1 more source
Self-Mutilation, Substance Abuse, and the Psychoanalytic Approach: Four Cases [PDF]
, 1998 Robert Waska
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