Results 171 to 180 of about 2,326,575 (402)
Regulation of Neuroinflammation by Microglial DUBA‐IRAK1‐IKKβ Signaling Loop
The protein levels of deubiquitinating enzyme A (DUBA) are rapidly upregulated in microglia after activation of Toll‐like receptor 4 (TLR4). In turn, DUBA potentiates TLR4‐induced proinflammatory signal transduction in microglia by stabilizing interleukin‐1 receptor activated kinase 1 (IRAK1) through K48 deubiquitination.
Zhenhu Zhu+22 more
wiley +1 more source
Incidence of Substance Abuse in the Workplace [PDF]
A survey of employers' attitudes regarding the prevalence of drugs in the workplace, how employee drug use impacts their firm, and the effectiveness of company policies to treat and prevent employee substance ...
core
Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim+9 more
wiley +1 more source
Objective: To evaluate emotion regulation as one of the important aspects of preventing and treatment of substance abuse. Materials and methods: This study had a quasi-experiment research method and a pretest-posttest design with the control group.
Afsaneh Shahbazirad, Mona Azizi
doaj
Cost-Benefit Analysis of Reclaiming Futures [PDF]
Assesses the costs of RWJF's initiative to improve substance abuse interventions for youth with improved service delivery, cooperation, and family involvement; estimates behavior change and reduction in juvenile crime; and considers returns on ...
core
Preventing Substance Abuse with American Indian Youth
Steven P. Schinke+6 more
openalex +1 more source
Knowledge and Attitudes of Registered Nurses Toward Perinatal Substance Abuse [PDF]
Cynthia S. Selleck, Barbara A. Redding
openalex +1 more source
A tailored bio‐targeted catalytic strategy based on a bacteria‐specific artificial biocatalyst (MoS2/Fe@mercaptophenylboronic acid@hyaluronic acid, MFBH) is proposed for treating bacterial endophthalmitis. This strategy exhibits high‐efficiency peptidoglycan‐targeted bactericidal efficacy in vivo following a single intravitreal injection of an ...
Caixia Sun+9 more
wiley +1 more source
Funding Cuts to Public Health in Massachusetts: Losses Over Gains [PDF]
Examines ten public health areas, from children's health to substance abuse, and describes the widening health disparities, reduced data collection, and other effects of budget cuts to programs in prevention, outreach, training, and technical ...
Deborah Klein Walker, Judith Kurland
core
Do substance abuse and mental health clients prefer automated assessments? [PDF]
Matthew G. Hile, Rita E. Adkins
openalex +1 more source