Results 41 to 50 of about 2,326,575 (402)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Patients’ experiences with coercive mental health treatment in Flexible Assertive Community Treatment: a qualitative study

BMC Psychiatry, 2023
Background Flexible Assertive Community Treatment (FACT) teams have been implemented in Norwegian health and social services over the last years, partly aiming to reduce coercive mental health treatment.
Eva Brekke, Hanne Clausen, Morten Brodahl, Anne S. Landheim   +3 more
doaj   +1 more source

The Link Between Intimate Partner Violence, Substance Abuse and Mental Health in California [PDF]

, 2011
Presents findings about how Californians who have been victims of intimate partner violence as adults are more likely to report serious psychological distress, violence-related substance abuse, and need for mental health and/or substance abuse ...
David Grant, Elaine Zahnd, May Jawad Aydin, Sue Holtby   +3 more
core  

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

Smoking among inpatients in treatment for substance use disorders: prevalence and effect on mental health and quality of life

BMC Psychiatry, 2021
Background Smoking is still prevalent among people with substance use disorders. The objective of this study was to investigate the prevalence of smoking among patients in treatment for substance use disorders and to analyze the effect of smoking both at
Lars Lien, Ingeborg Bolstad, Jørgen G. Bramness   +2 more
doaj   +1 more source

Guidelines for Organizing Art Exhibitions on Addiction and Recovery [PDF]

, 2009
Outlines the Innovators Combating Substance Abuse program's model for exhibiting art by those in addiction recovery as a way to offer insight into substance abuse and recovery.

core  

Individual and Environmental Factors Associated with Tobacco Smoking, Alcohol Abuse and Illegal Drug Consumption in University Students: A Mediating Analysis [PDF]

, 2020
[Abstract] Substance abuse is a major and prevalent public health concern among university students. Tobacco smoking, risky alcohol behavior, and illegal drug consumption may lead to health problems and behavioral and academic issues. Several individual
Cruz Valiño, José Manuel, Delgado-Lobete, Laura, Gándara Gafo, Berta, Montes-Montes, Rebeca, Santos-del-Riego, Sergio, Talavera Valverde, Miguel Ángel, Vila Paz, Alba   +6 more
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Using Goal Achievement Training in juvenile justice settings to improve substance use services for youth on community supervision

Health & Justice, 2018
Background The link between substance use and involvement in the juvenile justice system has been well established. Justice-involved youth tend to have higher rates of drug use than their non-offending peers.
Jacqueline Horan Fisher, Jennifer E. Becan, Philip W. Harris, Alexis Nager, Connie Baird-Thomas, Aaron Hogue, John P. Bartkowski, Tisha Wiley, The JJ-TRIALS Cooperative   +8 more
doaj   +1 more source

Stimulant ADHD medication and risk for substance abuse.

Journal of Child Psychology and Psychiatry and Allied Disciplines, 2014
BACKGROUND There are persistent concerns of long-term effects of stimulant ADHD medication on the development of substance abuse. METHODS Using Swedish national registers, we studied all individuals born between 1960 and 1998 and diagnosed with ADHD ...
Z. Chang, P. Lichtenstein, L. Halldner, B. D’Onofrio, E. Serlachius, S. Fazel, Niklas Långström, H. Larsson   +7 more
semanticscholar   +1 more source