Results 141 to 150 of about 246,416 (344)
Advanced Science, EarlyView.A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li +8 more
wiley +1 more source
Service Delivery in Substance Abuse Treatment: Reexamining "Comprehensive" Care [PDF]
, 2008 Outlines findings on organizational characteristics linked with comprehensive services -- core diagnosis and treatment and wraparound services, including transportation and childcare assistance or legal, financial, employment, or medical ...
Deanna Lewis, Lori J. Ducharme
core
Advanced Science, EarlyView.Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan +11 more
wiley +1 more source
The relationship between childhood trauma and patterns of alcohol and psychoactive substance use
Discover PsychologyObjective Millions of people lose their lives each year due to the effects of addiction, yet the role of childhood traumas in the roots of this problem is often overlooked.
Mehtap Sarıoğlu +2 more
doaj +1 more source
Reducing Infectious Diseases in the U.S.: Focus on HIV/AIDS and Hepatitis [PDF]
, 2009 Offers arguments for the efficacy of needle exchange programs in reducing infections among drug users and against the ban on using federal funds for such programs.
core
Advanced Science, EarlyView.This study presents a two‐color FCCS and coincident‐burst analysis platform to quantify actin cargo in dual‐labeled EVs secreted from hiPSCs. The approach tracks secretion dynamics, confirms actin loading, and measures EV size and cargo number, offering insights into cytoskeletal disruption and neuronal differentiation relevant to neurodegenerative ...
Dang Du Nguyen +4 more
wiley +1 more source
Research on Addiction, 2011 Purpose: This study compared the effectiveness of group cognitive-behavioral therapy based on coping skills (CBT) and methadone maintenance therapy (MMT) in improvement of emotional regulation strategies and prevention of relapse.
Tahereh Ghorbany +2 more
doaj
Advanced Science, EarlyView.Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen +12 more
wiley +1 more source
Substance Abuse of Crystal and Opium: Comparison of Marital Satisfaction and Anxiety
Salāmat-i ijtimā̒ī, 2017 Background: Substance abuse is the most common mental disorder in the present. This study aimed to compare marital satisfaction and anxiety in crystal, opium addicts with ordinary people do.
Ali Sarvestani +4 more
doaj