Results 111 to 120 of about 54,688 (241)

Using games to identify adolescents at risk for substance misuse-a proof-of-concept study. [PDF]

open access: yesFront Health Serv
Aneni K   +7 more
europepmc   +1 more source

Chronic alcohol consumption compromises gut barrier integrity and promotes endotoxemia: Implications for sepsis susceptibility in immunocompromised hosts

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Chronic alcohol exposure disrupts intestinal barrier integrity, resulting in a leaky gut and enhanced translocation of lipopolysaccharide (LPS) and microbial products into the systemic circulation. Alcohol‐induced endotoxemia drives exaggerated pro‐inflammatory responses, mitochondrial damage, and activation of the cGAS–STING pathway, particularly in ...
Thansita Bhunyakarnjanarat   +5 more
wiley   +1 more source

Animal research in the UK: Regulation, implementation, welfare and development of new approach methodologies

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Scientific research with animals in the UK is regulated by the Animals (Scientific Procedures) Act 1986 with the National Centre for the Replacement, Refinement and Reduction of Animals in Research providing support for best practice and facilitating development of new approach methodologies.
Ewan St. John Smith   +6 more
wiley   +1 more source

Conceptualising quality early childhood education: Learning from young children in Brazil and South Africa through creative and play‐based methods

open access: yesBritish Educational Research Journal, EarlyView., 2023
Abstract Early childhood has increasingly been acknowledged as a vital time for all children. Inclusive and quality education is part of the United Nations Sustainable Development Goals, with the further specification that all children have access to quality pre‐primary education.
Laura H. V. Wright   +8 more
wiley   +1 more source

DBT skills + parent training for preschool parents with emotion dysregulation and substance misuse. [PDF]

open access: yesBorderline Personal Disord Emot Dysregul
Everett Y   +9 more
europepmc   +1 more source

Lifetime Adversity Among Individuals With Early Phase Psychosis and Comorbid Substance Misuse. [PDF]

open access: yesEarly Interv Psychiatry
Patterson VC   +9 more
europepmc   +1 more source

Quantum Phenomena in Molecular and Biological Systems: A Decoherence‐Based Decision Framework With Falsifiable Predictions and a Failure‐Mode Taxonomy

open access: yesAdvanced Physics Research, EarlyView.
A physics‐grounded framework based on decoherence timescales (τ_dec vs τ_func), Markovian validity, and falsifiability criteria is applied across molecular systems to distinguish where quantum effects are necessary, marginal, or irrelevant. The analysis integrates quantum chemistry, biological quantum mechanisms, and quantum computing under a unified ...
Sarfaraz K. Niazi
wiley   +1 more source

Nontobacco Nicotine Dependence Is Associated With Perioperative Complications and Repeat Surgery After Arthroscopic Rotator Cuff Repair

open access: yesArthroscopy, EarlyView.
Purpose To compare perioperative complications and revision surgery rates between following primary rotator cuff repair among patients with nontobacco nicotine dependence (NTND), no nicotine dependence, and traditional tobacco‐related nicotine dependence.
Samuel A. Florentino   +6 more
wiley   +1 more source

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