Results 121 to 130 of about 53,729,253 (423)

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Entropy geometric construction of a pure substance with normal, superfluid and supersolid phases [PDF]

open access: yesarXiv, 2016
Using the laws of thermodynamics together with empirical data, we present a qualitative geometric construction of the fundamental relation of a pure substance $S = S(E,N,V)$, with $S$ entropy, $E$ energy, $N$ number of particles and $V$ volume. We analyze two very general type of substances, a "normal" and a "quantum" one, the main difference between ...
arxiv  

Complexity and asymptotic stability in the process of biochemical substance exchange in a coupled ring of cells [PDF]

open access: yes, 2013
We have considered the complexity and asymptotic stability in the process of biochemical substance exchange in a coupled ring of cells. We have used coupled maps to model this process. It includes the coupling parameter, cell affinity and environmental factor as master parameters of the model.
arxiv   +1 more source

Young substance use and substance use disorder in Chile: the role of the family [PDF]

open access: yes, 2021
As in other countries, Chilean youth-based treatments for justice-involved youths with substance use disorders need to find ways to obtain better results. One possibility is to involve family members in the intervention, thus we investigated family risk and protective factors for Chilean adolescents' substance use and substance use disorders.
openaire   +3 more sources

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

Substance Use Disorder Treatment Confidentiality Boot Camp [PDF]

open access: yes, 2017
[Excerpt]: INTRODUCTION: The Health Law and Policy Programs at UNH School of Law, Institute for Health Policy and Practice, and the NH Citizens Health Initiative have contracted with several of the New Hampshire Building Capacity for Transformation ...
Cameron, Stephanie   +4 more
core   +1 more source

Downeast Maine MAT Expansion Project: Year 3 Final Data Summary [PDF]

open access: yes, 2021
This report summarizes the collaborative effort of Healthy Acadia, its providers, the Downeast Substance Treatment Network, and Downeast Substance Use Response Coalition, to combat opioid use disorder (OUD) in Downeast Maine through multiple evidence ...
Ali, Evelyn, BS   +3 more
core   +1 more source

Is fentanyl in everything? Examining the unexpected occurrence of illicit opioids in British Columbia’s drug supply

open access: yesHarm Reduction Journal
Background Illicit opioids, including fentanyl, are linked to unprecedented levels of overdose in Canada and elsewhere. The risks associated with illicit opioids can include high potency, unpredictable concentration and the unexpected presence in other ...
Bruce Wallace   +12 more
doaj   +1 more source

Fentanyl assisted treatment: a possible role in the opioid overdose epidemic?

open access: yesSubstance Abuse Treatment, Prevention, and Policy, 2019
Background The current opioid overdose epidemic affecting communities across North America is increasingly driven by illicitly manufactured fentanyl and its related analogues.
Geoff Bardwell, Evan Wood, Rupinder Brar
doaj   +1 more source

Implementation opportunities and challenges identified by key stakeholders in scaling up HIV Treatment as Prevention in British Columbia, Canada: a qualitative study

open access: yesImplementation Science Communications, 2020
Background The province of British Columbia (BC), Canada, was among the first jurisdictions to scale up HIV Treatment as Prevention (TasP) to the population level, including funding and policy commitments that enhanced HIV testing efforts (e.g ...
Koharu Loulou Chayama   +4 more
doaj   +1 more source

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