Results 141 to 150 of about 54,964,175 (374)

Implementation opportunities and challenges identified by key stakeholders in scaling up HIV Treatment as Prevention in British Columbia, Canada: a qualitative study

open access: yesImplementation Science Communications, 2020
Background The province of British Columbia (BC), Canada, was among the first jurisdictions to scale up HIV Treatment as Prevention (TasP) to the population level, including funding and policy commitments that enhanced HIV testing efforts (e.g ...
Koharu Loulou Chayama   +4 more
doaj   +1 more source

122. Dalbavancin Use in Patients with Substance Use Disorders [PDF]

open access: gold, 2020
Amber C Streifel   +8 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Is fentanyl in everything? Examining the unexpected occurrence of illicit opioids in British Columbia’s drug supply

open access: yesHarm Reduction Journal
Background Illicit opioids, including fentanyl, are linked to unprecedented levels of overdose in Canada and elsewhere. The risks associated with illicit opioids can include high potency, unpredictable concentration and the unexpected presence in other ...
Bruce Wallace   +12 more
doaj   +1 more source

Changing patterns of first e-cigarette flavor used and current flavors used by 20,836 adult frequent e-cigarette users in the USA

open access: yesHarm Reduction Journal, 2018
Background Understanding the role that flavors play in the population’s use of e-cigarettes and the impact that flavored e-cigarette products have on the population’s use of more harmful tobacco products, like conventional cigarettes, has been identified
Christopher Russell   +3 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Delineating Patterns of Sexualized Substance use and its Association with Sexual and Mental Health Outcomes Among Young Gay, Bisexual and Queer Men in Singapore: A Latent Class Analysis [PDF]

open access: green, 2020
Rayner Kay Jin Tan   +9 more
openalex   +1 more source

Too much free time: Coos County Youth who are least involved in out-of-school activities are most likely to use drugs and alcohol [PDF]

open access: yes, 2010
Carsey Institute researchers are seeing links between the self-reported substance use and involvement in out-of-school activities. As part of a ten-year tracking survey of high school students in Coos County, New Hampshire, this brief finds that those ...
Sharp, Erin H.
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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