Results 161 to 170 of about 53,254,105 (402)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

An Assessment of Health Disparities among a Community Sample of LGBQ College Students [PDF]

open access: yes, 2018
Lesbian, gay, bisexual, and queer (LGBQ) individuals are a marginalized population in the United States, and this status places them at a greater risk for adverse health outcomes, such as tobacco and substance use, obesity, cancer, sexually-transmitted ...
Benotsch, Eric   +2 more
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

WORKPLACE SUBSTANCE USE, THE RISK OF OCCUPATIONAL INJURY, AND TESTING [PDF]

open access: yes, 2005
Over the past 20 years, the "workplace substance abuse prevention industry" has grown enormously in size and has become more sophisticated in its marketing approach. Drug testing alone has become a $6 billion industry.
Zimbardi, Guy
core  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Bereavement and Substance Use Disorder

open access: yes, 2018
In the present chapter, we focused on the relationship between bereavement and addiction, specifically among those patients who have a diagnosis of substance use disorder. Although bereavement research has advanced greatly in recent years, there are few studies on bereavement among the drug-dependent population.
Masferrer Boix, Laura   +1 more
openaire   +5 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Continuing care groups: long term treatment of substance use disorders [PDF]

open access: yes, 2014
Master's Project (M.Ed.) University of Alaska Fairbanks, 2014Substance use disorders are chronic diseases that affect individuals, families, and communities. These illnesses frequently require several courses of treatment to achieve abstinence. Inpatient
Foote, Olivia
core  

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