Results 211 to 220 of about 2,088,860 (358)

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Separation of fine biochemical substances using supercritical CO2 extraction.

, 1988
Masayoshi Kubota, Harumi Matsuzaki, Sankichi Takahashi   +2 more
openalex   +2 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Sleep phenotyping in a rat model of susceptibility to substance use disorders. [PDF]

PLoS One
Ficiarà E, Faniyan OO, Simayi R, Del Gallo F, Roberto M, Ciccocioppo R, Bellesi M, de Vivo L.   +7 more
europepmc   +1 more source

Studies on the Determination of Toxic Substances Using Solid Sorbent : (Rep. 4) Desorption Efficiency of Organic Solvents from a Passive Gas Sampler

, 1982
Toshifumi Ashida
openalex   +2 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

SAFETY ASSESSMENT AND MEASURES IN RESEARCH AND DEVELOPMENT OF SUBSTANCES USED FOR PHOTOGRAPHIC MATERIALS

, 1987
Takeshi Takahashi
openalex   +2 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Substance Use Disorder Treatment Outcomes: Methodological Overview of Metrics and Criteria. [PDF]

Int J Methods Psychiatr Res
Narváez-Camargo M, Lozano-Rojas O, Mancheño-Velasco C, Verdejo-García A.   +3 more
europepmc   +1 more source

Retention Behavior of Lipophilic Components in Biological Substances in Silica Gel Liquid Chromatography Using Aqueous Binary Solvent Systems

, 1989
Shoji Hara, Tatsuhiko Ando, Yoshiyuki Nakayama   +2 more
openalex   +2 more sources