Results 231 to 240 of about 2,231,194 (294)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Parents Use Online Communities to Seek Guidance on Child Substance Use, Parental Use, and Family Substance Use Challenges: A Content Analysis of Reddit Posts. [PDF]

J Stud Alcohol Drugs
Russell AM, Acuff SF, Litt DM, Kelly JF, Colditz JB, Valdez D, Allem JP.   +6 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Effectiveness of School-Based Resilience Interventions on Adolescent Tobacco, Alcohol, and Illicit Substance Use: A Meta-Analysis. [PDF]

J Sch Health
Chae J, Kim H.
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Protective Factors Against Violence and Substance Use in Adolescents: A Latent Class Analysis. [PDF]

J Adolesc Health
Szoko N, Joseph P, Hanner CD, Ramsey A, Mueller K, Miller E, Strotmeyer S, Culyba AJ.   +7 more
europepmc   +1 more source

What is the perceived relationship between boredom and substance use among persons who are unhoused? [PDF]

PLOS Ment Health
Herzog-Fequet C, Gewurtz R, Hansen N, Read H, Marshall C.   +4 more
europepmc   +1 more source

Externalized anger as a mediator of harsh parenting and substance use among Appalachian adolescents. [PDF]

Addict Behav Rep
Mills R, Tebes JK, Strambler MJ, Kristjansson AL.   +3 more
europepmc   +1 more source

Pharmacists expand access to contingency management in patients with substance use disorders. [PDF]

Ment Health Clin
Salsman M, Colvard M, Beam C, Frey T, Rothbauer K, Eatmon C.   +5 more
europepmc   +1 more source