Results 281 to 290 of about 53,729,253 (423)
Relationship Factors in Treating Substance Use Disorders [PDF]
Kelly, John+3 more
core +1 more source
Substance use among Ghanaian adolescents in secondary education: the determinants and medico-social implications. [PDF]
Appati W, Otupiri E, Appati A, Ntim EBO.
europepmc +1 more source
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
The Use and Physical Effects of Intravaginal Substances in Zairian Women
Richard C. D. Brown+2 more
openalex +1 more source
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
Clients' Experiences and Satisfaction with an Integrated Intensive Outpatient Program for Substance Use Disorders. [PDF]
Bador K+4 more
europepmc +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source