Results 61 to 70 of about 53,729,253 (423)

Predicting Individual Substance Abuse Vulnerability using Machine Learning Techniques [PDF]

arXiv, 2020
Substance abuse is the unrestrained and detrimental use of psychoactive chemical substances, unauthorized drugs, and alcohol. Continuous use of these substances can ultimately lead a human to disastrous consequences. As patients display a high rate of relapse, prevention at an early stage can be an effective restraint.
arxiv  

Identifying Chemicals Through Dimensionality Reduction [PDF]

arXiv, 2022
Civilizations have tried to make drinking water safe to consume for thousands of years. The process of determining water contaminants has evolved with the complexity of the contaminants due to pesticides and heavy metals. The routine procedure to determine water safety is to use targeted analysis which searches for specific substances from some known ...
arxiv  

Medication Treatment For Opioid Use Disorders In Substance Use Treatment Facilities.

Health Affairs, 2019
Medication treatment (MT) is one of the few evidence-based strategies proposed to combat the current opioid epidemic. We examined national trends and correlates of offering MT in substance use treatment facilities in the United States.
R. Mojtabai, Christine M Mauro, M. Wall, Colleen L. Barry, M. Olfson   +4 more
semanticscholar   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Illicit substance use among university students from seven European countries: A comparison of personal and perceived peer use and attitudes towards illicit substance use [PDF]

, 2014
Objective: To compare European students' personal use and approval of illicit substance use with their perceptions of peer behaviours and attitudes, and investigate whether perceptions of peer norms are associated with personal use of illicit substances ...
Ali, Arbour-Nicitopoulos, B. Vriesacker, B.M. Bewick, Berkowitz, Boot, Borsari, Buckner, C. Stock, European Monitoring Centre for Drugs, Drug Addiction (EMCDDA), European Monitoring Centre for Drugs, Drug Addiction (EMCDDA), European Monitoring Centre for Drugs, Drug Addiction (EMCDDA), F. Guillen-Grima, F. Salonna, G. Van Hal, H. Zeeb, Humeniuk, J. McAlaney, Kilmer, Kypri, Larimer, Lintonen, Martens, McAlaney, Neighbors, Neighbors, Page, Perkins, Perkins, Perkins, Perkins, Perkins, Pischke, Prince, R.C. Dempsey, R.T. Mikolajczyk, S.M. Helmer, UN Office on Drugs, Crime (UNODC), Wolfson, Y. Akvardar   +39 more
core   +1 more source

Lessons from the National institutes of health innovation corps program: defining barriers to developing and commercializing novel solutions for persons with opioid use disorder

Addiction Science & Clinical Practice
Background Translating innovative research advancements into commercially viable medical interventions presents well-known challenges. However, there is limited understanding of how specific patient, clinical, social, and legal complexities have further ...
Matthew P. Heshmatipour, Tyler M. Duvernay, Desislava Z. Hite, Eboo Versi, Michael P. Hite, David F. Reeser, Victor Prikhodko, Ariana M. Nelson, Bina Julian, Milton L. Greenberg   +9 more
doaj   +1 more source

Powering quantum Otto engines only with q-deformation of the working substance [PDF]

arXiv, 2023
We consider a quantum Otto cycle with a $q$-deformed quantum oscillator working substance and classical thermal baths. We investigate the influence of the quantum statistical deformation parameter $q$ on the work and efficiency of the cycle. In usual quantum Otto cycle, a Hamiltonian parameter is varied during the quantum adiabatic stages while the ...
arxiv  

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

The association of family and peer factors with tobacco, alcohol, and marijuana use among Chilean adolescents in neighborhood context [PDF]

, 2011
Research on adolescent use of substances has long sought to understand the family factors that may be associated with use of different substances such as alcohol, tobacco and marijuana.
Andrew Grogan-Kaylor, Cristina Bares, Jorge Delva, Pilar Horner, Pilar Horner   +4 more
core   +1 more source

Stimulant safe supply: a potential opportunity to respond to the overdose epidemic

Harm Reduction Journal, 2020
Background Occurring against the backdrop of an overdose crisis, stimulant use and stimulant-involved deaths in North America are increasing at an alarming rate.
Taylor Fleming, Allison Barker, Andrew Ivsins, Sheila Vakharia, Ryan McNeil   +4 more
doaj   +1 more source