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Substance Use Disorder

Emergency Medicine Clinics of North America
Substance use disorders (SUDs) present a challenge in the emergency department (ED) setting. This article provides an overview of SUDs, their clinical assessment, legal considerations in drug testing, diagnosis, and treatment approaches. SUDs are prevalent and coexist with mental health disorders, necessitating comprehensive evaluation and management ...
Kaitlyn R, Swimmer, Stephen, Sandelich
openaire   +2 more sources

Prevention of Substance Use Disorders

Medical Clinics of North America, 2022
Methods to prevent substance use disorders (SUDs) act on the individual risk factors for addiction. Most adults with SUD initiated substance use during their teenage years, so preventive interventions during adolescence are critical. Antisubstance use messaging, routine screening, and pathways for referral to treatment can be extended into all settings
Leah F, Nelson   +2 more
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GERIATRIC SUBSTANCE USE DISORDERS

Medical Clinics of North America, 1997
AUDs are increasingly recognized as common problems among older adults. The magnitude of this problem is likely to increase over ensuing decades as baby boomers reach retirement age with drinking habits that are significantly different from current cohorts of older adults. Barriers to detection are numerous and include nonspecificity of alcohol-related
M C, Reid, P A, Anderson
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Somatoform and Substance Use Disorders

Psychosomatic Medicine, 2007
To review the potential for diagnostic difficulties and overlap in a number of symptoms of somatoform disorders and symptoms of withdrawal from alcohol and drugs, and to review epidemiologic, family, and clinical studies addressing comorbidity between somatoform and substance use disorders. The comorbidity between somatoform disorders and substance use
Deborah, Hasin, Hila, Katz
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Biomarkers in Substance Use Disorders

ACS Chemical Neuroscience, 2015
The prevention and treatment of substance use disorders (SUDs), including addiction, would benefit from having better biomarkers for the classification of patients into categories that are reproducible and have predictive validity. Direct measurement of drugs or their metabolites in various body fluids constitutes a clinically valuable biomarker but ...
Nora D, Volkow   +2 more
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Genetics of Substance Use Disorders

Child and Adolescent Psychiatric Clinics of North America, 2016
Substance abuse disorders have a strong genetic component. Genetic risk factors associated with alcohol abuse include common variants in genes coding for alcohol-metabolizing enzymes and gamma-aminobutyric acid A receptors. Functional missense mutations in ADH1B and ALDH2 are protective against alcohol dependence.
Cassie, Yu, Jon, McClellan
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Substance Use Disorders Refresh: Nonopioid Substance Use Disorders

Psychiatric Services, 2023
Nan, Zhao   +2 more
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The patient with substance use disorder

Current Opinion in Anaesthesiology, 2019
The purpose of this review is to describe the anesthesiologist's perioperative challenges when caring for the patient with substance use disorder and, in particular, opioid use disorder.With the introduction of the fifth edition of Diagnostic and Statistical Manual of Mental Disorders, psychiatric literature recently changed the criteria for defining ...
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Neuroglia in substance use disorders

Substance use disorders (SUD) remain a major public health concern in which individuals are unable to control their use of substances despite significant harm and negative consequences. Drugs of abuse dysregulate major brain and behavioral functions. Glial cells, primarily microglia and astrocytes, play a crucial role in these drug-induced molecular ...
Emily M, Castro   +2 more
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Pharmacotherapy for Substance Use Disorders

Medical Clinics of North America, 2016
This article reviews the current pharmacotherapy options available for the treatment of patients with substance use disorders. In the United States there are medications available to treat tobacco use disorders (nicotine replacement, bupropion, and varenicline), alcohol use disorders (naltrexone and acamprosate), and opioid use disorders (methadone and
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