Results 101 to 110 of about 107,326 (259)

Bioethical considerations in the diagnosis and therapeutic treatment of drug dependence

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019
An updated bibliographic review was carried out using the resources available in Infomed, specifically Ebsco, PubMed and Scielo, by means of which the following databases were accessed: MEDLINE, Academic Search Premier, MedicLatina and Scopus.
Lilisbeth de la Caridad Benítez-Rojas, Rafael Alejandro Tamayo-Velázquez, Roberto Anselmo Ramos-Valverde   +2 more
doaj  

Brazilian guideline for the treatment of patients with opioids dependence syndrome [PDF]

, 2004
There is a relatively low prevalence of opioid use in Brazil, particularly involving the non-medical use of codeine and opiate-containing syrups. However, opioid dependence syndrome shows a significant total impact on mortality and morbidity.
Andrade, Arthur Guerra De, Baltieri, Danilo Antonio, Dias, João Carlos, Jerônimo, Cláudio, Malbergier, André, Nicastri, Sérgio, Scivoletto, Sandra, Strain, Eric C   +7 more
core   +4 more sources

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Optimal inference with suboptimal models:Addiction and active Bayesian inference [PDF]

, 2014
When casting behaviour as active (Bayesian) inference, optimal inference is defined with respect to an agent's beliefs - based on its generative model of the world.
Adams, Adams, Bechara, Beck, Beck, Belin, Berke, Berridge, Berridge, Bickel, Bishop, Blum, Blum, Blum, Bowers, Bowers, Brighton, Cain, Charness, Christoph Mathys, Clark, Clark, Comings, Conant, Daunizeau, Daw, Dayan, Dayan, Diana, Dolan, Doyon, Edwards, Everitt, Everitt, Eysenck, FitzGerald, Friedrich Wurst, Friston, Friston, Friston, Friston, Friston, Friston, Geisler, Gigerenzer, Gillan, Graybiel, Grether, Griffiths, Griffiths, Henden, Hommer, Jones, Kahnemann, Karl Friston, Kersten, Knill, Lee, MacKay, Mahmood, Maia, Martin Kronbichler, Miedl, Montague, Monterosso, Pellicano, Peters, Peters, Philipp Schwartenbeck, Pouget, Ray Dolan, Redish, Redish, Robinson, Schwartenbeck, Simon, Simon, Stephan, Story, Sutton, Taber, Tenenbaum, Thomas H.B. FitzGerald, Tversky, Tversky, Weiss, Whalley, Willuhn, Wolpert, Yu   +89 more
core   +2 more sources

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Nicotine-replacement therapy: A proven treatment for smoking cessation [PDF]

, 2010
Smoking is a major cause of cardiovascular diseases, respiratory diseases and cancer. Despite the high prevalence of smokers worldwide, smokers are often neglected and not offered effective assistance with quitting their habits. In order to overcome this
Robson, Noorzurani
core   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

National Disability Insurance Scheme and Quality of Life Among Carers of Children With Autism Spectrum Disorder in Australia: A Thematic Analysis

Australian Journal of Social Issues, EarlyView.
ABSTRACT Diagnoses of autism spectrum disorder in Australia have increased considerably in recent years. The current study investigated how the National Disability Insurance Scheme (NDIS) impacts quality of life (QoL) among carers of children with autism spectrum disorder.
Jesse Gerhard, Sharon L. Grant
wiley   +1 more source

The prevalence and clinical significance of inhalant withdrawal symptoms among a national sample

Substance Abuse and Rehabilitation, 2011
Brian E Perron1, Joseph E Glass2, Brian K Ahmedani3, Michael G Vaughn4, Daniel E Roberts1, Li-Tzy Wu51University of Michigan, Ann Arbor, MI, USA; 2Washington University, St Louis, MO, USA; 3Henry Ford Health System, Detroit, MI, USA; 4St Louis University,
Vaughn MG, Ahmedani BK, Glass JE, Perron BE, Roberts DE, Wu LT   +5 more
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