Results 191 to 200 of about 107,475 (276)

Documented End‐of‐Life Preferences of People With Parkinson's Disease or Parkinsonism Across Europe

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease and atypical parkinsonism are characterized by motor and non‐motor symptoms. As the disease advances, planning for end‐of‐life (EoL) care becomes increasingly important. However, consensus‐based European guidelines for advance care planning and documentation of EoL care preferences for parkinsonism are lacking ...
Bauke W. Dijkstra   +30 more
wiley   +1 more source

Considerations for Initiation and Maintenance of Foslevodopa/Foscarbidopa for Advanced Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background As Parkinson's disease (PD) progresses, motor fluctuations become increasingly difficult to manage with oral medications. Foslevodopa/foscarbidopa (LDp/CDp), delivered as a continuous 24‐h/day subcutaneous infusion, offers continuous levodopa delivery and stable plasma levodopa levels that reduce motor fluctuations. LDp/CDp has been
K. Ray Chaudhuri   +20 more
wiley   +1 more source

Risk‐Benefit Considerations in Deep Brain Stimulation Discontinuation for Late‐Stage Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Management of deep brain stimulation (DBS) in late‐stage Parkinson's disease (LSPD) remains challenging, particularly when deciding whether to continue or discontinue stimulation, and evidence on risk–benefit considerations is limited. Objectives To identify key factors to improve decision‐making in DBS management for LSPD patients.
Pietro Antenucci   +9 more
wiley   +1 more source

Evidence of heterogeneity in the opioid withdrawal syndrome: Spontaneous and precipitated withdrawal. [PDF]

open access: yesPharmacol Biochem Behav
Martinez S   +6 more
europepmc   +1 more source

The Impact of Participation in the Parkinson's Pals Program on Psychosocial Symptoms in Parkinson's Disease: An Unblinded Feasibility Study

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Persons with Parkinson's disease (pwPD) frequently experience psychosocial symptoms that are inadequately addressed by traditional clinical approaches. Objectives To evaluate the impact of Parkinson's Pals, a student‐led virtual, intergenerational program, on psychosocial symptoms in pwPD and student knowledge.
Jaskeerat Gujral   +4 more
wiley   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz   +2 more
wiley   +1 more source

CMAISE: Establishing the Longitudinal Multi‐Omics Cohort for Sepsis Precision Medicine

open access: yesMed Research, EarlyView.
ABSTRACT Sepsis remains a leading cause of mortality worldwide due to its profound biological heterogeneity. While multi‐omics approaches offer promise for precision medicine, existing datasets often lack longitudinal granularity or comprehensive clinical integration. We present the Chinese Multi‐omics Advances In Sepsis (CMAISE) cohort, a prospective,
Jie Yang   +36 more
wiley   +1 more source

The Diagnosis and Treatment of Stimulant-Related Emergencies. [PDF]

open access: yesDtsch Arztebl Int
Fries A   +5 more
europepmc   +1 more source

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