Results 201 to 210 of about 137,395 (319)

Prevalence of GHB-Related Presentations to a Metropolitan Emergency Department in Melbourne. [PDF]

Emerg Med Australas
Akhlaghi H, Maplesden J, Moon G, Pham E, Zurzolo F, Morrissey B, Norman A, Bonomo Y, Freeman S, Karro J.   +9 more
europepmc   +1 more source

Disease‐Modifying Trials in Treated Parkinson's Disease: “Stable Treated” Does Not Equate with Biological Stability

Movement Disorders, EarlyView.
Abstract Traditionally, clinical trials of putative disease‐modifying therapies in Parkinson's disease have enrolled untreated patients at the earliest clinical stages of their disease. Due to a number of challenges inherent with this approach, there has been a recent move to a different study design, enrolling patients who are already taking “stable ...
M. Maral Mouradian, A. Jon Stoessl, Anthony E. Lang   +2 more
wiley   +1 more source

Symptom-Triggered Alcohol Detoxification Compared to Fixed-Dose Regimen of Benzodiazepines: A Retrospective Case-Control Study. [PDF]

Brain Sci
Becciolini L, Wehrli F, Kronschnabel J, Wiesendanger C, Scherbaum N, Roser P.   +5 more
europepmc   +1 more source

Erythematous Papules and Plaques in an Infant Receiving Glucagon Therapy

JEADV Clinical Practice, EarlyView.
Sara Al Janahi, Alya Al‐Ali, Meera Al Adawi, Yusra S. Al Ali, Harish Bangalore   +4 more
wiley   +1 more source

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

Medicinal Research Reviews, EarlyView.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar, Tobias Werner, Mihajlo Gajic, Holger Stark, Bassem Sadek   +4 more
wiley   +1 more source

Reflections on the American Psychiatric Association 2025 Annual Meeting. [PDF]

Lancet Reg Health Am
Woolcott OO.
europepmc   +1 more source

Nutraceutical Blends Promote Weight Loss, Inflammation Reduction, and Better Sleep: The Role of Faecalibacterium prausnitzii in Overweight Adults–A Double‐Blind Trial

Molecular Nutrition &Food Research, EarlyView.
This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina, Victor Nehmi Filho, Jéssica Alves de Freitas, Lucas Augusto Moysés Franco, Roberta Cristina Martins, Joyce Vanessa Fonseca, José Antônio Orellana Turri, Mariana Tedesco Hufnagel, Daniel Pecoraro Demarque, Bruna Fernanda Rio Branco da Silva, Arianne Fagotti Gusmão, Eloísa Helena Ribeiro Olivieri, Erica de Souza, Esther Alves de Souza, José Pinhata Otoch, Ana Flávia Marçal Pessoa   +15 more
wiley   +1 more source

Treatments for Inhalant and Volatile Substance Misuse: A Scoping Review. [PDF]

Cureus
Lail G, Cornelio VC, Go K, Kaur K, Slowik P.   +4 more
europepmc   +1 more source

Minimal Clinically Important Differences in Measuring Treatment Effects in CIDP: History, Current Use, Limitations, and Prospects

Muscle &Nerve, EarlyView.
ABSTRACT Outcome measures are essential for evaluating treatment effects and disease progression in chronic inflammatory demyelinating polyneuropathy (CIDP). The concept of the minimal clinically important difference (MCID), which represents the smallest change in a measure deemed clinically meaningful, has become increasingly important in CIDP ...
Yusuf A. Rajabally, Kabir K. Nazeer, Young Gi Min   +2 more
wiley   +1 more source

Rapid intravenous symptom-inhibiting fentanyl induction (SIFI) to optimize rotation onto oral opioid agonist therapy among individuals who use unregulated fentanyl: protocol for an open-label, single arm clinical trial. [PDF]

Addict Sci Clin Pract
Azar P, Ignaszewski MJ, Harris M, Barazanci Z, Davison R, Wong JSH, Maharaj A, Mathew N, Hall D, Guillemi SA, Foreman J, Barrios R, Montaner JSG.   +12 more
europepmc   +1 more source