Results 301 to 310 of about 133,054 (344)
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Neuropathology of the Substantia nigra
European Neurology, 1991Neuronal subpopulations of the substantia nigra pars compacta can be separated into two functionally distinct nigrostriatal projections, the ventral tier which is poorly melanised, and the dorsal tier which is well melanised. In Parkinson's disease, juvenile-onset parkinsonism with dystonia and striatonigral degeneration the ventral tier is more ...
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Ontogeny of Substantia Nigra Dopamine Neurons
2009Understanding the ontogeny of A9 dopamine (DA) neurons is critical not only to determining basic developmental events that facilitate the emergence of the substantia nigra pars compacta (SNc) but also to the extraction and de novo generation of DA neurons as a potential cell therapy for Parkinson's disease.
R, Orme, R A, Fricker-Gates, M A, Gates
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Culture of Substantia Nigra Neurons
Current Protocols in Neuroscience, 1997AbstractPrimary cultures of nigral tissue are widely used as a model system to assay effects of trophic and toxic agents on dopaminergic neurons. Cultured dopaminergic neurons have been successfully transplanted in animals and led to behavioral improvement in animal models of Parkinson's disease.
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Neurotensin depolarizes substantia nigra dopamine neurones
Brain Research, 1985Neurotensin and the C-terminal 8-13 amino acid fragment were found to excite substantia nigra compacta dopamine neurones in vitro in a dose-dependent manner. The N-terminal 1-8 amino acid fragment was not active at the concentrations used. Desensitization was not observed.
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Substantia nigra Efferent Connections
Stereotactic and Functional Neurosurgery, 1979J M, Deniau +3 more
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