Results 61 to 70 of about 533,211 (252)

Equality, Self-determination, Administrative Discretion: Lessons from the Implementation of Jordan Principles in Two Provinces

Health Reform Observer - Observatoire des Réformes de Santé
Canada has an obligation to implement Jordan’s Principle in a way that achieves both substantive equality and self-determination. Both these principles require an approach that centres the full participation of First Nations, supports the development ...
Vandna Sinha, Josée G. Lavoie
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

About us: equality in a diverse Ireland

, 1999
The Equality Authority is an independent body set up under the Employment Equality Act 1998. It was established on 18th October 1999. Policy is decided by the Board of the Equality Authority.The Board is appointed by the Minister for Justice, Equality
Equality Authority (EA)
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Annual Report 2009 - The Equality Authority

, 2010
The Equality Authority ...
The Equality Authority
core  

Recognizing Substantive Equality as a Foundational Constitutional Principle [PDF]

, 1999
The author proposes that substantive equality be recognized as a foundational constitutional principle. The foundational principles--or underlying constitutional norms-which constitute the constitutional framework have become more important as Canada ...
Hughes, Patricia
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

The Importance of Being Earnest: Spelling of Names, EU Citizenship and Fundamental Rights

Croatian Yearbook of European Law and Policy, 2015
Names are central elements of people’s identities: they distinguish them from other individuals and play an important role in human self-determination. Names and their spelling reach, from time to time, national and European courtrooms.
Adam Lazowski, Egle Dagilyte, Panos Stasinopoulos   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Equality Plans in Andalusian Universities: Professional Promotion Policies

Education Sciences
In recent decades, Equality Plans have played a pivotal role in promoting substantive gender equality in academia, particularly in terms of professional advancement and the reduction in gender gaps.
Pilar Ibáñez-Cubillas, Mercedes Cuevas-López, Susana de las Nieves Stoner   +2 more
doaj   +1 more source