Results 91 to 100 of about 67,257 (300)

Further application of dual substituent parameter and dual substituent parameter-non-linear resonance methods in modelling ¹³C substituent chemical shifts in β-substituted styrenes

, 1988
Dual substituent parameter and dual substituent parameter-non-linear resonances analysis have been successfully applied to model the long-range substituent effect on 13C substituent chemical shifts (SCS) in eight series of β-substituted styrenes, each ...
Bhattacharyya, Sankar Prasad, Brunskill, John S. A., Medhi, Chitrani, Chakravarty, Ajit Kumar, Datta, Sumana, Fadoujou, Solomon, Fish, Kenneth, De, Asish   +7 more
core   +1 more source

Metal (n+1)p‐nd Orbital Hybridization and Excited‐State Metal–Ligand π‐Interactions Enable d10 Carbene‐Metal‐Amide TADF OLEDs with High Efficiency and Long Operational Lifetime

Advanced Science, EarlyView.
We elucidate the key roles of metal p‐d orbital hybridization, excited‐state metal–ligand π‐interactions, and structural rotation in TADF of d10 CMA complexes. Introducing electron‐withdrawing or π‐extended ligand substituents weakens excited‐state metal‐ligand π‐interactions and improves kTADF, but may compromise emitter stability in device operation.
Shuo Xu, Rui Tang, Qingyun Wan, Gang Cheng, Jun Yang, Chi‐Ming Che   +5 more
wiley   +1 more source

Chemometrical Analysis of Substituent Effects. V. ortho Effect

, 1994
The dissociation constants of nineteen ortho substituted benzoic acids have been determined in eight organic solvents (methanol, ethanol, acetone, dimethyl sulfoxide, dimethylformamide, acetonitrile, pyridine, 1,2-dichloroethane). The correlation between
Josef Liška, Oldřich Pytela
core   +1 more source

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

Advanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng, Peipei Wang, Pengfei Wang, Jiamin Wang, Baiyang Li, Daqing Fang, Jian He, Xiaobei Hu, Weijuan Kan, Yubo Zhou, Chunpu Li, Jia Li, Hong Liu   +12 more
wiley   +1 more source

H-Bonding-Assisted Substituent Effect

, 2016
In this paper we investigate the influence of intramolecular noncovalent interaction, i.e., H-bonding and Li-bonding, on the properties of substituents communicating through the resonance (mesomeric) effect in such molecular systems as salicylaldehyde, o-
Marcin Palusiak (1472365), Tadeusz M. Krygowski (1763227), Joanna E. Zachara-Horeglad (2277796)   +2 more
core   +1 more source

Structural Substituent Effect in the Excitation Energy of aChromophore: Quantitative Determination and Application toS-Nitrosothiols [PDF]

, 2012
A methodology for the prediction of excitation energies for substituted chromophores on the basis of ground state structures has been developed. The formalism introduces the concept of ?structural substituent excitation energy effect?
Fernández González, Miguel Ángel, Frutos Gaite, Luis Manuel, Zapata Ruiz, Felipe, Marazzi, Marco Dino Maurizio, Temprado Morena, Manuel, Rivero Fernández, Daniel, García Iriepa, Cristina, López Delgado, Alberto, Castaño González, Obis Dionisio   +8 more
core   +1 more source

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source

Dual-Emissive Monoruthenium Complexes of N(CH₃)-Bridged Ligand: Synthesis, Characterization, and Substituent Effect. [PDF]

Materials (Basel), 2023
Wu SH, Zhang Z, Zheng RH, Yang R, Wang L, Shao JY, Gong ZL, Zhong YW.   +7 more
europepmc   +1 more source

Heterogeneous Visible‐Light Photocatalysis in Continuous‐Flow: A Synergistic Strategy for Challenging Trifluoromethylation of α, α‐Diaryl Allylic Alcohols via 1,2‐aryl Migration

Advanced Science, EarlyView.
A continuous‐flow photocatalytic strategy is presented for the efficient synthesis of β‐trifluoromethyl ketones under visible light. Using a recyclable solid photocatalyst and an inexpensive CF3 source, the method enables rapid reactions, easy scale‐up, and smooth integration into multistep flow synthesis of bioactive molecules.
Peiwen Liu, Weiping Zhu, Xuhong Qian, Fang Zhao   +3 more
wiley   +1 more source

Nucleophilic Substitution on 2-Monosubstituted Quinoxalines Giving 2,3-Disubstituted Quinoxalines: Investigating the Effect of the 2-Substituent

Molecules, 2016
An investigation on the effect of substituent at the 2-position of mono-substituted quinoxalines in the synthesis of di-substituted quinoxaline derivatives via nucleophilic substitution reactions, is reported.
Ndumiso Thamsanqa Ndlovu, Winston Nxumalo   +1 more
doaj   +1 more source