Results 41 to 50 of about 9,469,736 (295)

Substituent-Dependent Negative Hyperconjugation in 2-Aryl-1,3-N,N-heterocycles. Fine-Tuned Anomeric Effect?

, 2016
The epimerization reactions of conformationally inflexible 2-aryl-1,3-N,N-heterocycles were used as model systems to study the role of the nitrogen lone pair-C2 associated antibonding orbital hyperconjugative interactions in the experimentally observed ...
László Lázár (2716390), Tamás A. Martinek (146462), Ferenc Fülöp (2468881), Zita Zalán (3035112), Anasztázia Hetényi (146434)   +4 more
core   +2 more sources

ESI-MS spectra of 3-cyano-4-(substituted phenyl)-6-phenyl-2(1H)-pyridinones [PDF]

Journal of the Serbian Chemical Society, 2009
Twelve 3-cyano-4-(substituted phenyl)-6-phenyl-2(1H)-pyridinones were investigated by tandem mass spectrometry using positive as well as negative electrospray ionization.
BRATISLAV Ž. JOVANOVIĆ, MILA D. LAUŠEVIĆ, TATJANA M. VASILJEVIĆ, ALEKSANDAR D. MARINKOVIĆ   +3 more
doaj   +3 more sources

Effect of substituent position on assembly of compounds bearing ortho/para over meta directing groups

Results in Chemistry
This research investigated the impact of substituent location on intermolecular interactions and crystal packing. A class of N-(dichlorophenyl)-2-pyrazincarboxamide derivatives were synthesized and characterized: 2,5-dichloro (2,5-diCl), 3,4-dichloro (3 ...
Vahid Amani, Fataneh Norouzi, Maryam Esmaeili, Hamid Reza Khavasi   +3 more
doaj   +1 more source

Substituent-Driven Selective N/OAlkylation of 4(Trihalomethyl)pyrimidin-2(1H)ones Using Brominated Enones

, 2022
The selective N- or O-alkylation of 4-(tri­halo­methyl)­pyrimidin-2­(1H)-ones, using 5-bromo enones/enaminones as alkylating agents, is reported. It was found that the selectivity toward the N- or O-regioisomer is driven by the substituent present at the
Ludger A. Wessjohann, Genilson S. Pereira (12238850), Marcos A. P. Martins, Nilo Zanatta, Helio G. Bonacorso (1457209), Mateus Mittersteiner (6899375), Mateus Mittersteiner, Yuri Silva, Helio G. Bonacorso, Marcos A. P. Martins (9155491), Nilo Zanatta (1457224), Yuri Silva (12238853), Ludger A. Wessjohann (578796), Genilson S. Pereira   +13 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Substituent-Modulated Assembly Formation: An Approach to Enhancing the Photostability of Photoelectric-Sensitive Chalcogenide-Based Ion-Pair Hybrids

, 2017
A series of electronically active viologen dications (RV) with tunable substituent groups were utilized to hybridize with [Ge4S10]4– (T2 cluster) to form the hybrids of T2@RV.
Zhixing Fu (2573122), Jiaxu Zhang (1942288), Yujia Zhu (3800539), Dongsheng Li (222712), Dandan Hu (2823056), Tao Wu (16763), Jian Lin (323268)   +6 more
core   +2 more sources

Substituent Effects on the Photophysical Properties of a Series of 8(meso)-Pyridyl-BODIPYs: A Computational Analysis of the Experimental Data

Physchem
Recently, a series of 8(meso)-pyridyl-BODIPYs (2-pyridyl, 3-pyridyl, and 4-pyridyl) and their 2,6-substituted derivatives were synthesized and their structure and photophysical properties were studied both experimentally and computationally.
Petia Bobadova-Parvanova, Dylan Goliber, Elijuah Hernandez, Daniel LaMaster, Maria da Graça H. Vicente   +4 more
doaj   +1 more source

Substituent Effect Study for 13C SCS in a Meta-Styrene Series. Reynolds Dual Substituent Parameter Model Investigation

, 2021
This article investigates the transmission of the meta-substituent, X, effect to the carbon β (Cβ) of 17 different styrenes (X–C6H4–CHCYZ) using the literature 13C substituent chemical shift (SCS) of Cβ.
Basil A. Saleh (1973284), Ghazwan F. Fadhil (11377661), Sabih A. Al-Shawi (11377658), Basil A. Saleh, Sabih A. Al-Shawi, Ghazwan F. Fadhil   +5 more
core   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Insight into Spodium–π Bonding Characteristics of the MX₂⋯π (M = Zn, Cd and Hg; X = Cl, Br and I) Complexes—A Theoretical Study

Molecules, 2022
The spodium–π bonding between MX2 (M = Zn, Cd, and Hg; X = Cl, Br, and I) acting as a Lewis acid, and C2H2/C2H4 acting as a Lewis base was studied by ab initio calculations. Two types of structures of cross (T) and parallel (P) forms are obtained.
Meng Gao, Qibo Zhao, Hao Yu, Min Fu, Qingzhong Li   +4 more
doaj   +1 more source