Results 31 to 40 of about 9,273,531 (285)

A survey on the characterization and biological activity of isatin derivatives [PDF]

Journal of the Serbian Chemical Society, 2020
The derivatives of isatin have already been known to display a variety of biological activities. Therefore, the studies on their activity and its relation to structure have recently become a popular subject for investigation.
Drmanić Saša Ž., Petrović Predrag, Brkić Dominik R., Marinković Aleksandar D., Nikolić Jasmina B.   +4 more
doaj   +1 more source

A Computational Investigation of the Substituent Effects on Geometric, Electronic, and Optical Properties of Siloles and 1,4-Disilacyclohexa-2,5-dienes

Molecules, 2017
Thirty two differently substituted siloles 1a–1p and 1,4-disilacyclohexa-2,5-dienes 2a–2p were investigated by quantum chemical calculations using the PBE0 hybrid density functional theory (DFT) method.
Aleksandra V. Denisova, Julius Tibbelin, Rikard Emanuelsson, Henrik Ottosson   +3 more
doaj   +1 more source

Substituent effects in triarylphosphines [PDF]

, 2012
M.Sc. The main objective of the work presented in this dissertation was to investigate the application of the phosphorus atom as a probe to evaluate stereo-electronic effects in arylphosphines. Traditionally, electronic effects are described as having inductive or resonance origins.
Renison, Carina Alicia
openaire   +2 more sources

Synthesis, Evaluation of Substituent Effect and Antimicrobial Activities of Substituted (E)-1-(3-bromo-4-morpholinophenyl)-3-phenylprop-2-en-1-one Compounds

Orbital: The Electronic Journal of Chemistry, 2017
A series of ten substituted (E)-1-(3-bromo-4-morpholinophenyl)-3-phenylprop-2-en-1-one compounds were synthesized by Crossed-Aldol condensation of 3-bromo-4-marpholino acetophenone with various substituted and unsubstituted benzaldehydes in presence of ...
Selvaraj Balaji, Murugan Rajarajan, Renganathan Vijayakumar, Venkatesan Manikandan, Rajamohan Senbagam, Ganesan Vanangamudi, Ganesamoorthy Thirunarayanan   +6 more
doaj   +3 more sources

The substituent effect on benzene dications

Phys. Chem. Chem. Phys., 2014
It was shown that the substituent effect in the dicationic benzene ring, which is a 4 n π-electron system, can be numerically quantified and then further interpreted.
Palusiak, Marcin, Domagala, Malgorzata, Dominikowska, Justyna, Bickelhaupt, F. Matthias   +3 more
openaire   +5 more sources

Substituent Effects on the Stability of Thallium and Phosphorus Triple Bonds: A Density Functional Study

Molecules, 2017
Three computational methods (M06-2X/Def2-TZVP, B3PW91/Def2-TZVP and B3LYP/LANL2DZ+dp) were used to study the effect of substitution on the potential energy surfaces of RTl≡PR (R = F, OH, H, CH3, SiH3, SiMe(SitBu3)2, SiiPrDis2, Tbt (=C6H2-2,4,6-(CH(SiMe3 ...
Jia-Syun Lu, Ming-Chung Yang, Ming-Der Su   +2 more
doaj   +1 more source

Energetics of Electron Pairs in Electrophilic Aromatic Substitutions

Molecules, 2021
The interacting quantum atoms approach (IQA) as applied to the electron-pair exhaustive partition of real space induced by the electron localization function (ELF) is used to examine candidate energetic descriptors to rationalize substituent effects in ...
Julen Munárriz, Miguel Gallegos, Julia Contreras-García, Ángel Martín Pendás   +3 more
doaj   +1 more source

Hydrogen rearrangement in molecular ions of alkyl benzenes: Appearance potentials and substituent effects on the formation of [C7H8]+ ions [PDF]

, 1978
Kuck D, Grützmacher H-F. Hydrogen rearrangement in molecular ions of alkyl benzenes: Appearance potentials and substituent effects on the formation of [C7H8]+ ions. Organic Mass Spectrometry.
Grützmacher, Hans-Friedrich, Kuck, Dietmar   +1 more
core   +1 more source

Substituent and structural effects on the kinetics of the reaction of N-(substituted phenylmethylene)-m- and -p-aminobenzoic acids with diazodiphenylmethane [PDF]

Journal of the Serbian Chemical Society, 2007
The rate constants for the reaction of twenty-two N-(substituted phenylmethylene)- m- and -p-aminobenzoic acids with diazodiphenylmethane were determined in absolute ethanol at 30 °C.
Jovanović Bratislav Ž., Marinković Aleksandar D., Vitnik Željko, Juranić Ivan O.   +3 more
doaj   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source