Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
, 2022 The protection of confidential information is a global issue and block encryption algorithms are the most reliable option for securing data. The famous information theorist, Claude Shannon has given two desirable characteristics that should exist in a ...
Mohmmad Mazyad Hazzazi +5 more
core +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
CONSTRUCTION OF SUBSTITUTION BOX (S-BOX) BASED ON IRREDUCIBLE POLYNOMIALS ON GF(2^8)
BarekengIn the field of modern encryption algorithms, the creation of S-Box is an essential element that plays an important role in maintaining data security in various industries.
Faldy Tita +2 more
doaj +1 more source
Derivation of the Hicks Elasticity of Substitution from the Input Distance Function [PDF]
The Hicks or direct elasticity of substitution is traditionally derived from the production function. This paper exploits duality theory to present a more general derivation from the input distance function, which is exactly dual to the Shadow Elasticity
Stern, David I.
core
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Environmental impact assessment of battery boxes based on lightweight material substitution
Scientific ReportsPower battery is one of the core components of electric vehicles (EVs) and a major contributor to the environmental impact of EVs, and reducing their environmental emissions can help enhance the sustainability of electric vehicles. Based on the principle
Xinyu Li +3 more
doaj +1 more source
A Cross-Country Estimation of the Elasticity of Substitution between Labor and Capital in Manufacturing Industries [PDF]
This paper presents a simple methodology to estimate the elasticity of substitution between labor and capital for firms operating in perfectly competitive factor markets with constant-elasticity-of-substitution technologies.
Sebastián Claro
core
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
A highly nonlinear substitution-box (S-box) design using action of modular group on a projective line over a finite field. [PDF]
PLoS One, 2020 Siddiqui N +7 more
europepmc +1 more source