Results 101 to 110 of about 1,575,632 (331)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

OTQuSbox Framework: A Quantum-Assisted Session-Based S-Box Construction With Secure Seed Synchronization

open access: yesIEEE Access
Conventional Substitution-boxes (S-boxes) used in symmetric-key cryptography are typically static or generated through deterministic pseudo-random processes, making them vulnerable to long-term structural analysis, precomputation, and learning-based ...
Annas W. Malik   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Currency substitution in the transition economy: a case of the Czech Republic 1993-2001 [PDF]

open access: yes, 2001
Currency substitution appears to be an important issue affecting the design of monetary policy, especially in transition economies. Therefore, this paper strives to analyze the particular relevance of a currency substitution phenomenon for the Czech ...
Komárek, Luboš, Melecky, Martin
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Currency substitution and money demand in Euroland [PDF]

open access: yes
This papers tests the stability of the demand for money in the euro area in the context of an open economy. A sample consisting of quarterly data covering the 1982:2-1999:3 period is considered.
Miguel Lebre de Freitas
core  

A Boy and a Box: Winning Race Car

open access: yes, 2020
Winning Race Car Stoneware with Glaze 6” x 6” x 6” 2020 The next thing he makes is a race car, which is currently on top of a mound of blankets, with small cars surrounding him. This piece symbolizes that creating can also be a wild journey. The creative
Carper, Jacalyn
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Dollarization and Euroization in Transition Countries: Currency Substitution, Asset Substitution, Network Externalities and Irreversibility [PDF]

open access: yes
We examine the extent, causes and consequences of transition countries’ use of foreign currency as a co-circulating medium of exchange and store of value.
James Dean, Edgar Feige
core  

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