Results 41 to 50 of about 130,050 (259)
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
The double random phase encoding (DRPE) system plays a significant role in encrypted systems. However, it is a linear system that leads to security holes in encrypted systems.
Peiran Tian, Runzhou Su
doaj +1 more source
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier +11 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
An In-Depth Analytical Cryptanalysis for Substitution Boxes: Odd Size Case Study
From hieroglyphic writing in ancient Egypt to the post-quantum edge, cryptology is usually seen as an immortal concept that evolves within the enhancement of human civilization.
Ismail El Gaabouri +3 more
doaj +1 more source
A novel design for the construction of safe S-boxes based on TDERC sequence
The focus of this article is to construct substitution box based on tangent delay for elliptic cavity chaotic sequence and a particular permutation of symmetric group of permutations. The analysis result shows that the proposed S-box is very good against
Ali Hussain Alkhaldi +2 more
doaj +1 more source
Relating Undisturbed Bits to Other Properties of Substitution Boxes [PDF]
Recently it was observed that for a particular nonzero input difference to an S-Box, some bits in all the corresponding output differences may remain invariant. These specific invariant bits are called undisturbed bits. Undisturbed bits can also be seen as truncated differentials with probability \(1\) for an S-Box.
Rusydi H. Makarim, Cihangir Tezcan
openaire +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Evolving Dynamic S-Boxes Using Fractional-Order Hopfield Neural Network Based Scheme
Static substitution-boxes in fixed structured block ciphers may make the system vulnerable to cryptanalysis. However, key-dependent dynamic substitution-boxes (S-boxes) assume to improve the security and robustness of the whole cryptosystem.
Musheer Ahmad, Eesa Al-Solami
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

