Results 51 to 60 of about 136,267 (257)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
IoT enabled data protection with substitution box for lightweight ciphers
Egyptian Informatics JournalRapid growth in communication and networking demands the protection of highly sensitive data in the system. The cryptographic techniques used in various traditional devices and cloud environments are not applicable to resource-constrained devices like ...
K.B. Sarmila, S.V. Manisekaran
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A novel design for the construction of safe S-boxes based on TDERC sequence
Alexandria Engineering Journal, 2015 The focus of this article is to construct substitution box based on tangent delay for elliptic cavity chaotic sequence and a particular permutation of symmetric group of permutations. The analysis result shows that the proposed S-box is very good against
Ali Hussain Alkhaldi +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Cryptanalysis of Novel Image Encryption Scheme Based on Multiple Chaotic Substitution Boxes
IEEE Access, 2021 In current years many chaos-based Substitution boxes (S-boxes) have been proposed. Recently, an image encryption technique based on multiple chaotic S-box was offered.
Ammar S. Alanazi +4 more
doaj +1 more source
Construction of Substitution Boxes Using Finite Fields
VFAST Transactions on Mathematics, 2023 Substitution boxes (S-boxes) play a crucial role in modern cryptographic algorithms, providingnon-linear transformations that enhance the security of data encryption. S-boxes are essentialcomponents of symmetric key ciphers, such as Advanced Encryption Standard (AES) and DataEncryption Standard (DES).
Naveed Ahmed Umrani +2 more
openaire +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source