Results 51 to 60 of about 482,791 (290)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Energy substitution, technical change and rebound effects [PDF]

, 2014
This paper investigates the relationships between energy efficiency improvements by producers, the ease of substitution between energy and other inputs and the size of the resulting “rebound effects”.
Allan, Apostolakis, Azar, Berndt, Berndt, Berndt, Berndt, Bhattacharyya, Binswanger, Blackorby, Bosetti, Broadstock, Burniaux, Christensen, Conrad, Edenhofer, Frondel, Frondel, Frondel, Frondel, Gerlagh, Glomsrod, Goulder, Grepperud, Hanley, Hertel, Hicks, Hogan, Hogan, Kemfert, Kemfert, Kermfert, Koetse, Lecca, Löschel, Manne, Manne, Manne, Manne, McFadden, Patterson, Popp, Raj, Sanstad, Sato, Sato, Saunders, Saunders, Saunders, Saunders, Saunders, Saunders, Sorrell, Stern, Steve Sorrell, Sue Wing, Sue Wing, Sue Wing, Turner, Van der Werf, Van der Zwaan   +60 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An In-Depth Analytical Cryptanalysis for Substitution Boxes: Odd Size Case Study

Engineering Proceedings
From hieroglyphic writing in ancient Egypt to the post-quantum edge, cryptology is usually seen as an immortal concept that evolves within the enhancement of human civilization.
Ismail El Gaabouri, Mostafa Belkasmi, Mohamed Senhadji, Brahim El Bhiri   +3 more
doaj   +1 more source

A novel design for the construction of safe S-boxes based on TDERC sequence

Alexandria Engineering Journal, 2015
The focus of this article is to construct substitution box based on tangent delay for elliptic cavity chaotic sequence and a particular permutation of symmetric group of permutations. The analysis result shows that the proposed S-box is very good against
Ali Hussain Alkhaldi, Iqtadar Hussain, Muhammad Asif Gondal   +2 more
doaj   +1 more source

Evolving Dynamic S-Boxes Using Fractional-Order Hopfield Neural Network Based Scheme

Entropy, 2020
Static substitution-boxes in fixed structured block ciphers may make the system vulnerable to cryptanalysis. However, key-dependent dynamic substitution-boxes (S-boxes) assume to improve the security and robustness of the whole cryptosystem.
Musheer Ahmad, Eesa Al-Solami
doaj   +1 more source

Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]

, 2013
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Alt, Volker, Gelinsky, Michael, Hanke, Thomas, Hartmann, Sonja, Heinemann, Sascha, Heiss, Christian, Kampschulte, Marian, Kauschke, Vivien, Kautz, Armin R., Kilian, Olaf, Langheinrich, Alexander, Lips, Katrin Susanne, Ray, Seemun, Schnabelrauch, Matthias, Schnettler, Reinhard, Schumacher, Matthias, Thormann, Ulrich   +16 more
core   +2 more sources

A Site-Specific Synthetic Route to Substituted Inda(box) Ligands

Organic Letters, 2023
Aminoindanol-derived bis(oxazoline) ligands are widely used in metal-catalyzed transformations, but the synthesis of structural derivatives is challenging. We report the gram-scale, seven-step synthesis of five bromine-functionalized in-da(box) ligands that have varied bridge substituents.
Kimberly A. Alley, Aidan J. Clarkson, Ayaka Uehara, Jeffrey S. Johnson   +3 more
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

An Innovative Design of Substitution-Boxes Using Cubic Polynomial Mapping [PDF]

Symmetry, 2019
In this paper, we propose to present a novel technique for designing cryptographically strong substitution-boxes using cubic polynomial mapping. The proposed cubic polynomial mapping is proficient to map the input sequence to a strong 8 × 8 S-box meeting the requirements of a bijective function. The use of cubic polynomial maintains the simplicity of S-
Zahid, Amjad Hussain, Arshad, Muhammad Junaid   +1 more
openaire   +1 more source