Results 81 to 90 of about 2,477,868 (369)

Twisted multifilament superconductor [PDF]

open access: yes, 1973
Masking selected portions of a ribbon and forming an intermetallic compound on the unmasked portions by a controlled diffusion reaction produces a twisted filamentary structure.
Coles, W. D.
core   +1 more source

Fbxw7 regulates Notch to control specification of neural precursors for oligodendrocyte fate

open access: yesNeural Development, 2012
BackgroundIn the developing vertebrate nervous system elevated levels of Notch signaling activity can block neurogenesis and promote formation of glial cells.
Julia L. Snyder   +2 more
semanticscholar   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Substrate specificity of bleomycin hydrolase

open access: yesBiochemical Pharmacology, 1989
Bleomycin (BLM) hydrolase is believed to protect both malignant and normal tissue from the toxicity of the antitumor drug BLM. Little is known about the substrate specificity of BLM hydrolase. Thus, we developed ion-paired reverse phase high speed liquid chromatography systems to assay for the metabolism of several BLM analogs.
S M, Sebti   +4 more
openaire   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Cell Mechanics in Embryoid Bodies

open access: yesCells, 2020
Embryoid bodies (EBs) resemble self-organizing aggregates of pluripotent stem cells that recapitulate some aspects of early embryogenesis. Within few days, the cells undergo a transition from rather homogeneous epithelial-like pluripotent stem cell ...
Kira Zeevaert   +3 more
doaj   +1 more source

Substrate Specificity of Trypanothione Reductase [PDF]

open access: yesEuropean Journal of Biochemistry, 1997
Trypanothione redutase, one of the family of flavin‐dependent disulfide oxidoreductases, catalyses the reduction of trypanothione disulfide [N1,N8‐bis(glutathionyl)spermidine] and related glutathionyl‐polyamine disulfides. A series of subtly different, designed substrate analogues based on trypanothione were prepared by means of a solid‐phase approach ...
I R, Marsh, M, Bradley
openaire   +2 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Developmentally-Inspired Biomimetic Culture Models to Produce Functional Islet-Like Cells From Pluripotent Precursors

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Insulin-producing beta cells sourced from pluripotent stem cells hold great potential as a virtually unlimited cell source to treat diabetes. Directed pancreatic differentiation protocols aim to mimic various stimuli present during embryonic development ...
Raymond Tran   +4 more
doaj   +1 more source

On orbit validation of solar sailing control laws with thin-film spacecraft [PDF]

open access: yes, 2017
Many innovative approaches to solar sail mission and trajectory design have been proposed over the years, but very few ever have the opportunity to be validated on orbit with real spacecraft. Thin- Film Spacecraft/Lander/Rovers (TF-SL Rs) are a new class
Baoyin, H   +4 more
core  

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