Cryo-EM structure of GH43 β-Xylosidase from Enterobacter cloacae provides insights into substrate specificity and the role of an auxiliary domain in enzymatic activity. [PDF]
FEBS JBriganti L +8 more
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
The C-terminal lectin-like domain modulates the substrate specificity and transglycosylation activity of rice β-galactosidase1 (<i>Os</i>BGal1). [PDF]
PeerJChoknud S +5 more
europepmc +1 more source
Advanced Engineering Materials, EarlyView.A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora +4 more
wiley +1 more source
Structural basis for substrate specificity and MSMEG_0435-0436 binding by the mycobacterial long-chain acyl-CoA carboxylase complex. [PDF]
Proc Natl Acad Sci U S ALiang Y, Bueler SA, Rubinstein JL.
europepmc +1 more source
Advanced Engineering Materials, EarlyView.Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios +5 more
wiley +1 more source
A method for predicting enzyme substrate specificity residues using homologous sequence information. [PDF]
Protein SciMori S, Niide T, Toya Y, Shimizu H.
europepmc +1 more source
Advanced Engineering Materials, EarlyView.Copper‐based composites enhanced with carbon feature convenient mechanical properties and favorable electric conductivity. Processing via deformation and thermomechanical treatments can introduce advantageous microstructures further enhancing their performance. Herein, copper–graphene powder‐based composites are directly consolidated via rotary swaging
Radim Kocich +3 more
wiley +1 more source
Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity. [PDF]
Cell RepWilkinson E +12 more
europepmc +1 more source
Advanced Engineering Materials, EarlyView.Mass density governs the protective behavior of oxide layers on nuclear fuel cladding. Ptychographic X‐ray computed tomography measures zirconium oxide grown on Zircaloy‐4 under reactor and autoclave conditions, revealing nearly identical bulk densities of 5.1 ± 0.80 g cm−3.
Okan Yetik +9 more
wiley +1 more source