Results 71 to 80 of about 660,873 (335)

Substrate Specificity and Enzymatic Characteristics of Three Rutinosidases

open access: yesShipin gongye ke-ji
Quercetin, naringenin, and hesperetin are the hydrolysis products of rutinoside flavonoids, known for their multiple biological activities and potential applications.
Fengwei XIAO   +4 more
doaj   +1 more source

The response of a macromolecule near a tiled substrate [PDF]

open access: yesJournal of Engineering Sciences 11 (4), 43-48 (2020), 2020
We analyze response of a macromolecule near to a substrate; the substrate is tiled in the sequential and specific manner so that repeat units of the macromolecule may have different response on its adsorption in different directions onto the substrate.
arxiv  

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Substrate specificity of the cypemycin decarboxylase CypD

open access: yesSynthetic and Systems Biotechnology, 2018
The linaridin antibiotic cypemycin is a ribosomal synthesized and post-translationally modified peptide (RiPP) that possesses potent activity against mouse leukemia cells.
Wei Ding   +3 more
doaj  

Block-based characterization of protease specificity from substrate sequence profile

open access: yesBMC Bioinformatics, 2017
Background The mechanism of action of proteases has been widely studied based on substrate specificity. Prior research has been focused on the amino acids at a single amino acid site, but rarely on combinations of amino acids around the cleavage bond ...
Enfeng Qi   +4 more
doaj   +1 more source

Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase

open access: yesNature Communications, 2020
Core-fucosylation of the N-glycan core is an essential biological modification and the α1,6- fucosyltransferase FUT8 is the only enzyme in humans that catalyses this modification through the addition of an α-1,6-linked fucose to N-glycans.
Ana García-García   +6 more
doaj   +1 more source

Rational engineering of an elevator-type metal transporter ZIP8 reveals a conditional selectivity filter critically involved in determining substrate specificity

open access: yesCommunications Biology, 2023
Engineering of transporters to alter substrate specificity as desired holds great potential for applications, including metabolic engineering. However, the lack of knowledge on molecular mechanisms of substrate specificity hinders designing effective ...
Yuhan Jiang   +8 more
doaj   +1 more source

Pure competition of multiple species during mixed-substrate microbial growth: Extending the resource-based theory [PDF]

open access: yesarXiv, 2005
The simultaneous growth of multiple microbial species is a problem of fundamental ecological interest. In media containing more than one growth-limiting substrate, multiple species can coexist. The question then arises: Can single-species data predict the existence and stability of mixed-culture steady states in mixed-substrate environments?
arxiv  

Atomized Spraying of Liquid Metal Droplets on Desired Substrate Surfaces as a Generalized Way for Ubiquitous Printed Electronics [PDF]

open access: yes, 2013
A direct electronics printing technique through atomized spraying for patterning room temperature liquid metal droplets on desired substrate surfaces is proposed and experimentally demonstrated for the first time. This method has generalized purpose and is highly flexible and capable of fabricating electronic components on any desired target objects ...
arxiv   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy