Results 91 to 100 of about 5,430,598 (303)

Simulation and optimization of temperature field of diamond coated tools deposited by HFCVD method based on heat dissipation at tool bottom

Jin'gangshi yu moliao moju gongcheng, 2020
In the process of preparing diamond coated tools by a hot filament chemical vapor deposition (HFCVD) method, substrate temperature has an important effect on the uniformity of diamond coating distribution.
QIAN Yizheng, ZHANG Tao, WANG Shu, CHEN Dakui, HUANG Guodong   +4 more
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

SYNTHESIS AND OPTICAL–STRUCTURAL CHARACTERIZATION OF ZNS THIN FILMS DEPOSITED VIA SPRAY PYROLYSIS [PDF]

Acta Scientifica Malaysia
Mature Zinc sulphide (ZnS) thin films are promising materials for optoelectronic and photovoltaic devices due to their wide band gap and high transparency.
Adebayo Samuel, Babatola Babatude.Keji, Adeolu Ajide, Abiona Mujidat Ayobami, Olushola Ebenezer Oluwatobi   +4 more
doaj   +1 more source

Zinc phthalocyanine — Influence of substrate temperature, film thickness, and kind of substrate on the morphology

Thin Solid Films, 2011
Abstract Zinc phthalocyanine (ZnPc), C32H16N8Zn, is a planar organic molecule having numerous optical and electrical applications in organic electronics. This work investigates the influence of various deposition parameters on the morphology of vapour thermal evaporated ZnPc films.
Schünemann, C, Elschner, C, Levin, A, Levichkova, M, Leo, K, Riede, M   +5 more
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Modifying the nanostructure and the mechanical properties of Mo2BC hard coatings: Influence of substrate temperature during magnetron sputtering

Materials & Design, 2018
A reduction in synthesis temperature is favorable for hard coatings, which are designed for industrial applications, as manufacturing costs can be saved and technologically relevant substrate materials are often temperature-sensitive.
Stephan Gleich, Rafael Soler, Hanna Fager, Hamid Bolvardi, Jan-Ole Achenbach, Marcus Hans, Daniel Primetzhofer, Jochen M. Schneider, Gerhard Dehm, Christina Scheu   +9 more
doaj   +1 more source

Silicon–carbon films deposited at low substrate temperature

Journal of Non-Crystalline Solids, 2006
Films composed of Si crystallites embedded in an amorphous silicon-carbon matrix have been deposited at low temperature by PECVD onto Corning glass and SnO2:F coated glass substrates. An increase of RF power from 15 to 100 W reduces the silicon crystalline fraction and enhances the carbon content in the amorphous material, causing the crystalline to ...
AMBROSONE, GIUSEPPINA, COSCIA, UBALDO, S. LETTIERI, MADDALENA, PASQUALINO MARIA, M. DELLA NOCE, S. FERRERO, S. RESTELLO, V. RIGATO, M. TUCCI   +8 more
openaire   +6 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source