Results 161 to 170 of about 1,396,264 (316)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Machine learning-assisted molecular design for efficient ¹⁹F hyperpolarization. [PDF]

Chem Sci
Peng Q, Zheng L, Sun H, Xiong Y, Zheng Z, Cui X, Chen Z, Wang X.   +7 more
europepmc   +1 more source

Potentiometric sensing of butyrylcholinesterase based on in situ generation and detection of substrates

, 2009
A novel reagentless biosensor has been developed in which the traditional ion selective electrode is used as a controlled-release system for in situ generation and detection of enzyme ...
Ding, JW, Ding, Jiawang, Qin, W, Qin, Wei   +3 more
core  

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Robots and Minimal, Physics-Informed Features: A Hybrid Framework for Enzyme Catalysis. [PDF]

Adv Sci (Weinh)
Onishchenko N, Larsen ES, Paneru G, Lee K, Kolygina DV, Jia Y, Clarissa EM, Wong WS, Grzybowski BA.   +8 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Novel thin film composite membranes supported by cellulose triacetate porous substrates for high-performance forward osmosis

, 2018
Novel thin film composite forward osmosis (TFC-FO) membranes were developed by using hydrophilic cellulose triacetate (CTA) porous substrates prepared by thermally induced phase separation (TIPS) method.
Gu, Lin, Xu, Zhi-Kang, Xing, Xiao-Yan, Yu, Yuan, Wu, Qing-Yun   +4 more
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Interfacial Engineering of Dual-Layer Au-Shelled Ag Nanowires: Decoupling Chemical Stability From Ultrasensitive Surface-Enhanced Raman Spectroscopy Activity. [PDF]

Small Sci
Li Y, Jafari A, Lin D, Palisaitis J, Yi Y, Pedersen JO, Duan Y, Persson POÅ, Jonsson MP, Ederth T, Tybrandt K.   +10 more
europepmc   +1 more source