Results 161 to 170 of about 2,340,556 (352)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Substrate selection of the caprellid Caprella dilatata (Crustacea, Amphipoda) [PDF]

, 2011
Mariana Baptista Lacerda, Setuko Masunari   +1 more
openalex   +1 more source

Lettuce types development and substrate fertility attributes in response to doses of an aerobic biofertilizer

, 2023
Catharine Abreu Bomfim, Mariana Rodrigues Fontenelle, Marcos Brandão Braga, Daniel Basílio Zandonadi, Juscimar da Silva, I. M. R. Guedes, Helson Mário Martins do Vale, Carlos Eduardo Pacheco Lima   +7 more
openalex   +2 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Diffusion in a quasi-one-dimensional system on a periodic substrate [PDF]

, 2012
João Cláudio Nunes Carvalho, K. Nelissen, W. P. Ferreira, G. A. Farias, F. M. Peeters   +4 more
openalex   +1 more source

Au(I)-catalyzed cycloaddition pathways of non-terminal propargyl substrates [PDF]

, 2020
Huey‐San Melanie Siah, Helgi Freyr Jónsson, Anne Fiksdahl   +2 more
openalex   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Gold nanoparticle arrays using pre-patterned silicon substrates. [PDF]

Discov Nano
Schmidl G, Diegel M, Li W, Gawlik A, Schmidl F, Dellith J, Hübner U, Plentz J.   +7 more
europepmc   +1 more source

Do changes in riparian zones affect periphyton growth and invertebrate colonization on rocky substrates in Atlantic Forest streams?

, 2018
Walace P. Kiffer, Thais Zanotti Giuberti, Karoline Victor Serpa, Flávio Mendes, Marcelo S. Moretti   +4 more
openalex   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source