Results 31 to 40 of about 846,630 (268)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Growth of Leucaena leucocephala (Lam.) de Wit favored by organic waste in the Brazilian semiarid region

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental
The aim of this study was to evaluate the effect of sources and rates of organic waste and their interaction on the growth of Leucaena leucocephala (Lam.) de Wit, in the Southeast region of Piauí State. The treatments consisted of two sources (Copernicia
Francisco H. C. Amaral   +4 more
doaj   +1 more source

Polyoxometalates on Functional Substrates: Concepts, Synergies, and Future Perspectives

open access: yesAdvanced Science, 2020
Polyoxometalates (POMs) are molecular metal oxide clusters that feature a broad range of structures and functionalities, making them one of the most versatile classes of inorganic molecular materials.
Alexey S. Cherevan   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Lifetime Analysis of Commercial 3 W UV-A LED

open access: yesCrystals, 2020
The lifetime of ultraviolet high-power light-emitting diodes (UV HP-LEDs) is an open issue due to their high current density, high temperature, and UV radiation.
F. Jose Arques-Orobon   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Contribution to seed ecology of Sequoiadendron giganteum (Lindl.) Buchholz growing in the Central European conditions

open access: yesJournal of Forest Science, 2018
The properties of Giant Sequoia (Sequoiadendron giganteum (Lindley) Buchholz) seeds originating from a single cultivated Sequoia tree in the second gene strain in the Czech Republic were examined. The maximum germination level was set at 1.8%.
Hana PRKNOVÁ
doaj   +1 more source

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