Results 41 to 50 of about 846,630 (268)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
We investigated the residual efficacy of four insecticide formulations used in Chagas disease vector control campaigns: cyfluthrin 12.5% suspension concentrace (SC), lambda-cyhalothrin 10% wettable powder (WP), deltamethrin 2.5% SC, and 2.5% WP on four ...
Antonieta Rojas de Arias +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Analysis of residual stresses in bioinert inorganic plasma sprayed ceramic coatings / Анализ остаточных напряжений в биоинертных неорганических керамических покрытиях, нанесенных плазменным напылением / Analiza zaostalih napona u bioinertnim neorganskim keramičkim plazma sprej prevlakama [PDF]
One of the factors for a successful application of ceramic coatings on biomedical implants is the compatibility of the physical and mechanical properties of coatings with the metal substrates of implants.
Mihailo R. Mrdak
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Mitogen-activated protein kinase (MPK) cascades are essential signal transduction components that control a variety of cellular responses in all eukaryotes.
Sunghwa Bahk +7 more
doaj +1 more source
O crescente uso de substratos na produção agrícola e no cultivo em ambiente protegido, promove produção em grande escala. Nesse sentido, as caracterizações químicas, biológicas e físicas desses materiais se fazem necessárias à proposição e à avaliação de
Roger Manuel Mestas Valero +2 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Objetivou-se estudar substratos e adubação em plantas de orquídea da espécie C. loddgesii "Alba" x C. loddgesii "Atibaia". Plantas oriundas de cultivo in vitro foram transplantadas para bandejas coletivas contendo pó de xaxim e aclimatizadas em casa de ...
Aparecida Gomes de Araujo +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

