Results 61 to 70 of about 1,396,264 (316)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Mitogen-activated protein kinase (MPK) cascades are essential signal transduction components that control a variety of cellular responses in all eukaryotes.
Sunghwa Bahk +7 more
doaj +1 more source
O crescente uso de substratos na produção agrícola e no cultivo em ambiente protegido, promove produção em grande escala. Nesse sentido, as caracterizações químicas, biológicas e físicas desses materiais se fazem necessárias à proposição e à avaliação de
Roger Manuel Mestas Valero +2 more
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Objetivou-se estudar substratos e adubação em plantas de orquídea da espécie C. loddgesii "Alba" x C. loddgesii "Atibaia". Plantas oriundas de cultivo in vitro foram transplantadas para bandejas coletivas contendo pó de xaxim e aclimatizadas em casa de ...
Aparecida Gomes de Araujo +4 more
doaj +1 more source
EFFECT OF SUBSTRATES ON OYSTER MUSHROOM PRODUCTION [PDF]
A Thesis Submitted to the Department of Horticulture, Faculty of Agriculture, Sher-e-Bangla Agricultural University, Dhaka in partial fulfillment of the requirement for the degree of MASTER OF SCIENCE (MS ...
ASHA, ISMOTARA
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A grápia (Apuleia leiocarpa) apresenta dificuldades de propagação via sementes, devido a sua germinação demorada e irregular, causada pela impermeabilidade do tegumento.
Fernando Teixeira Nicoloso +3 more
doaj +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Camellia shells are the main by-product of camellia seed processing and are usually incinerated or disposed of as agricultural waste. In this study, camellia shells were employed in the Pleurotus pulmonarius cultivation process using five distinct ...
Yikai Huang +5 more
doaj +1 more source

