Results 141 to 150 of about 502,362 (345)

Preoperative Functional Connectivity Predicts Antiparkinson Drug Change after Deep Brain Stimulation

Movement Disorders, EarlyView.
Abstract Background Deep brain stimulation (DBS) can effectively ameliorate motor symptoms in Parkinson's disease (PD), but patient outcomes remain variable. Clinical predictors lack reliability and only explain a small proportion of outcome variance, outlining a need for biomarkers that can enhance prediction accuracy.
David Mikhael, Skyler Deutsch, Juhi Mehta, Sarah Wang, John Kornak, Philip A. Starr, Jill L. Ostrem, Doris D. Wang, Ian O. Bledsoe, Melanie A. Morrison   +9 more
wiley   +1 more source

Mirthful laughter induced by subthalamic nucleus stimulation

Movement Disorders, 2001
AbstractHigh‐frequency stimulation of the subthalamic nucleus (STN) improves the motor signs of Parkinson's disease (PD). The three main components (motor, associative, and limbic) of the cortical‐basal ganglia‐cortical circuits pass through the STN. It is not known whether STN stimulation can influence the limbic loop.
Krack, Paul, Kumar, Rajeev, Ardouin, Claire, Dowsey, P. L., McVicker, John, Benabid, Alim-Louis, Pollak, Pierre   +6 more
openaire   +4 more sources

How to run a brain bank. A report from the Austro-German brain bank [PDF]

, 1993
The sophisticated analysis of and growing information on the human brain requires that acquisition, dissection, storage and distribution of rare material are managed in a professional way.
Gsell, W., Heckers, S., Heinsen, H., Jellinger, K., Lange, Klaus W., Pfeuffer, R., Ransmayr, G., Senitz, D., Vock, R., Wichart, I.   +9 more
core  

Morphological Changes in Direct Pathway Striatal Neurons in a Rat Model of Tardive Dyskinesia

Movement Disorders, EarlyView.
Abstract Background Tardive dyskinesia (TD) and drug‐induced parkinsonism (DIP) arise from prolonged dopamine antagonist use. Although D2 receptor hypersensitivity in the indirect pathway is a proposed mechanism, the role of the direct pathway remains unclear.
Hiroki Hikichi, Haruo Nishijima, Fumiaki Mori, Iku Kinoshita, Chieko Suzuki, Koichi Wakabayashi, Masahiko Tomiyama   +6 more
wiley   +1 more source

Being Guided by Your Brain or by Your Heart? Challenges in Adaptive Deep Brain Stimulation

Movement Disorders Clinical Practice, EarlyView.
Mario Sousa, Gerd Tinkhauser
wiley   +1 more source

Longitudinal Blood‐Biomarker‐Based Assessment of Brain Injury in Patients Undergoing Deep Brain Stimulation and Magnetic Resonance–Guided Focused Ultrasound

Movement Disorders, EarlyView.
Abstract Background Deep brain stimulation (DBS) and magnetic resonance–guided focused ultrasound (MRgFUS) are associated with neuroaxonal damage and astroglial activation; yet their extent and timing remain unclear despite clinical relevance for monitoring and outcome assessment.
Justina Dargvainiene, Ann‐Kristin Helmers, Juliana Naumann, Carl Alexander Gless, Bettina Möller, Julius Welzel, Frank Leypoldt, Johannes Hensler, Ina Tesseur, Klaus‐Peter Wandinger, Günther Deuschl, Daniela Berg, Steffen Paschen   +12 more
wiley   +1 more source

Transcranial Ultrasound Stimulation of Internal Globus Pallidus Region and Motor Cortex in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Many patients with Parkinson's disease (PD) have motor impairments despite dopaminergic therapy. Low‐intensity transcranial ultrasound stimulation (TUS) is a non‐invasive neuromodulation method with high spatial precision. The effects of motor cortex (M1) and internal globus pallidus (GPi) TUS on PD motor signs and cortical ...
Yi‐Ying Lin, Nasem Raies, Talyta Grippe, Carolyn A. Gunraj, Can Sarica, Utpal Kumar Saha, Amitabh Bhattacharya, Ghazaleh Darmani, Robert Chen   +8 more
wiley   +1 more source

Does Impaired Plantar Cutaneous Vibration Perception Contribute to Axial Motor Symptoms in Parkinson’s Disease? Effects of Medication and Subthalamic Nucleus Deep Brain Stimulation

, 2023
Tobias Heß, Peter Themann, Christian Oehlwein, Thomas L. Milani   +3 more
openalex   +2 more sources

Measuring activity of the subthalamic nucleus in acute slices using multi electrode arrays [PDF]

, 2009
The symptoms of Parkinson’s disease (a.o.: tremor, rigidity) can be suppressed by electrical stimulation of the basal ganglia. The most common target nucleus of this so called Deep Brain Stimulation (DBS) is the subthalamic nucleus (STN).
Heida, T., Stegenga, J.
core   +1 more source

Another Microlesion Effect after STN‐DBS for Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Atsushi Umemura, Genko Oyama, Kenya Nishioka, Nobutaka Hattori   +3 more
wiley   +1 more source