Results 131 to 140 of about 335,108 (249)

Speech Biomarkers for Quantifying Effects of Subthalamic Deep Brain Stimulation in Parkinson's Disease

Annals of Neurology, Volume 100, Issue 3, Page 628-640, September 2026.
Objective Dysarthria is one of the most common and disabling side effects of subthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson's disease (PD). Stimulation often exacerbates speech dysfunction beyond the effects of PD progression, likely because of current spread to structures surrounding the STN.
Petr Krýže, Mário Sousa, Vojtěch Illner, Adriana Jorge, Matilde Castelli, Ines Debove, Andreia D. Magalhães, Julia Waskönig, Lenard Lachenmayer, Joan Philipp Michelis, Gerd Tinkhauser, Deborah Amstutz, Marie Elise Maradan‐Gachet, Katrin Petermann, Claudio Pollo, Tobias Nef, Paul Krack, Jan Rusz   +17 more
wiley   +1 more source

Coherent spike-wave oscillations in the cortex and subthalamic nucleus of the freely moving rat.

, 2005
The basal ganglia play a critical role in controlling seizures in animal models of idiopathic non-convulsive (absence) epilepsy. Inappropriate output from the substantia nigra pars reticulata (SNr) is known to exacerbate seizures, but the precise ...
Sharott, A, Brown, Peter, Meissner, W, Magill, PJ, Kupsch, A, Brown, P, Harnack, D   +6 more
core   +1 more source

Crosstalk Between Cortical Plasticity and Peripheral Nervous Injury: Insights, Mechanisms, and Future Directions

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Peripheral nerve injury induces dynamic cortical plasticity, driven by molecular mechanisms such as BDNF and neurotransmitter systems. This review synthesizes subtype‐specific plasticity patterns: compressive injuries trigger rapid reorganization, while metabolic neuropathies lead to maladaptive changes.
Cong Cheng, Dong Gao, Yaojie Shen, Xi Wang, Junxi Dai, Yaoxian Xiang, Zongyuan Jiang, Zongqi You, Junjian Jiang   +8 more
wiley   +1 more source

Subthalamic nucleus involvement in children: A neuroimaging pattern-recognition approach

, 2014
A neuroimaging-based pattern-recognition approach has been shown to be very helpful in the diagnosis of a wide range of pediatric central nervous system diseases.
Huisman, Thierry A G M, Huisman, Thierry A.G.M., Anghelescu, Cristina, Johnston, Michael V, Poretti, Andrea, Craiu, Dana, Bosemani, Thangamadhan, Johnston, Michael V., Boltshauser, Eugen, Pearl, Phillip L., Boltshauser, Eugen; https://orcid.org/, Pearl, Phillip L, Hoon Jr, Alexander H, Hoon, Alexander H   +13 more
core   +1 more source

Auditory oddball responses in the human subthalamic nucleus and substantia nigra pars reticulata

Neurobiology of Disease
The auditory oddball is a mainstay in research on attention, novelty, and sensory prediction. How this task engages subcortical structures like the subthalamic nucleus and substantia nigra pars reticulata is unclear.
Dallas Leavitt, Frhan I. Alanazi, Tameem M. Al-Ozzi, Melanie Cohn, Mojgan Hodaie, Suneil K. Kalia, Andres M. Lozano, Luka Milosevic, William D. Hutchison   +8 more
doaj   +1 more source

Unveiling Functional Architecture of Human Thalamus: AStereoelectroencephalography Study

MedComm, Volume 7, Issue 9, September 2026.
The human thalamo‐cortical loop underpins complex behavior and is implicated in a wide range of neurological and psychiatric disorders, yet its functional organization remains incompletely understood. Using direct electrical stimulation combined with the human functional connectome, we mapped the functional architecture of the human thalamus and ...
Liankun Ren, Di Wu, Cuiping Xu, Lei Qi, Guangyuan Jin, Xueyuan Wang, Yueyang Cheng, Jialin Du, Siyi Wang, Dongmei Hu, Junliang Ge, Yixi Zheng, Yihe Wang, Huaqiang Zhang, Yang Dai, Hao Yan, Runshi Gao, Ying Gao, Zeyu Zhang, Penghu Wei, Yuping Wang, Philippe Kahane, Fabrice Bartolomei, Tao Yu, Guoguang Zhao   +24 more
wiley   +1 more source

From Skull Density Ratio‐based eligibility to efficiency‐informed planning: Predictive modeling of thermal response in MR‐guided focused ultrasound

Medical Physics, Volume 53, Issue 9, September 2026.
Abstract Background Transcranial MR‐guided focused ultrasound (MRgFUS) enables incisionless thermoablation of deep brain targets and has become an established modality in functional neurosurgery. Treatment efficiency is strongly influenced by skull‐mediated ultrasound attenuation.
José Angel Pineda‐Pardo, Jaime Caballero‐Insaurriaga, Marta Castillo‐Ortiz, Miguel López‐Aguirre, Rafael Rodríguez‐Rojas, Jorge U. Máñez‐Miró, Michele Matarazzo, Marta Del Alamo, Raul Martínez‐Fernández   +8 more
wiley   +1 more source

Subthalamic nucleus lesions: widespread effects on changes in gene expression induced by nigrostriatal dopamine depletion in rats

, 1995
Lesions of the subthalamic nucleus block behavioral effects of nigrostriatal dopamine depletion in rats and primates, but the contribution of this region to the molecular effects of dopaminergic lesions is unknown.
MF Chesselet, JM Delfs, TJ Parry, VM Ciaramitaro   +3 more
core   +1 more source

Resting State Functional Connectivity Among Cortical and Subcortical Grey Matter Structures Can Distinguish Fallers in Parkinson's Disease

European Journal of Neuroscience, Volume 64, Issue 5, September 2026.
In 58 people with Parkinson's disease, fallers showed weaker resting‐state connectivity between the left dorsolateral prefrontal cortex and hypothalamus, and between somatosensory cortex and globus pallidus internus. Combining these measures discriminated fallers from nonfallers, identifying potential targets for fall prevention. The figure was created
Rodrigo Vitorio, Korey P. Wylie, Justin W. Andrushko   +2 more
wiley   +1 more source

Bidirectional EEG Neurofeedback of Sensorimotor Beta Oscillations Reveals Asymmetric Modulation and Strategy‐Dependent Learning

European Journal of Neuroscience, Volume 64, Issue 5, September 2026.
Healthy participants performed EEG‐based neurofeedback (ENF) to modulate sensorimotor beta activity. Most successfully decreased beta, few increased it and learning varied by strategy, engagement and fatigue. Early ENF performance reflects effortful, strategy‐driven control rather than stable neurophysiological change, challenging binary ‘responder ...
Krithika Anil, Stephen Hall, Jennifer A. Freeman, Jonathan Marsden, Giorgio Ganis   +4 more
wiley   +1 more source