Results 111 to 120 of about 17,967 (218)

Freezing of Gait Levodopa Response Pattern in Parkinson's Disease Provides Clues to Pathophysiology

European Journal of Neuroscience, Volume 64, Issue 1, July 2026.
ABSTRACT Freezing of gait (FOG) is a common and enigmatic feature of Parkinson's disease (PD) because of its episodic and unpredictable nature. It is now clear that FOG is not a monolithic phenomenon but instead exhibits substantial heterogeneity across patients, suggesting the existence of subtypes.
Stewart A. Factor, David Weinshenker, Jeanne Powell, Andrew S. Monaghan, Daniel S. Peterson, J. Lucas Mckay   +5 more
wiley   +1 more source

Pharmacologically Modulating the Noradrenergic Arousal System to Reduce Freezing of Gait in Parkinson's Disease: Study Protocol of the International AnTi‐FREEZE Study

European Journal of Neuroscience, Volume 64, Issue 2, July 2026.
The AnTi‐FREEZE study follows a three‐visit protocol consisting of a baseline visit and two randomized crossover visits with atomoxetine or placebo. Assessments in dopaminergic OFF‐ and ON‐states examine the effect of atomoxetine on freezing of gait severity and the role of noradrenaline in the pathophysiology of freezing of gait.
Franka M. Goossens, Kaylena A. Ehgoetz Martens, Bastiaan R. Bloem, Rick C. Helmich, Erika E. Howe, Roy P. C. Kessels, Melvyn Roerdink, Annie G. Bryant, James M. Shine, Anouk Tosserams, Simon J. G. Lewis, Jorik Nonnekes   +11 more
wiley   +1 more source

Visible Tongue Fasciculations With Electromyographic Denervation in Autopsy‐Proven Progressive Supranuclear Palsy Mimicking Amyotrophic Lateral Sclerosis

Muscle &Nerve, Volume 74, Issue 2, Page 496-499, August 2026.
Hiroyasu Inoue, Yoshihiko Horimoto, Yo Tsuda, Yuta Madokoro, Shoji Kawashima, Akio Akagi, Yasushi Iwasaki, Noriyuki Matsukawa   +7 more
wiley   +1 more source

The Subthalamic Nucleus Controls Action Timing under Threat. [PDF]

eNeuro
Zhou J, Sajid MS, Hormigo S, Castro-Alamancos MA.   +3 more
europepmc   +1 more source

Piezoelectric neuromodulation of the subthalamic nucleus ameliorates motor and nonmotor symptoms of Parkinson's disease. [PDF]

Sci Adv
Zhao D, Zhong G, Cao Z, Io WF, Guo F, Cui J, Qu L, Hao J, Shi L, Xie J.   +9 more
europepmc   +1 more source

Impact of subthalamic nucleus deep brain stimulation on voice and speech in Parkinson's disease. [PDF]

Eur Arch Otorhinolaryngol
Tuysuz O, Hasimoglu O, Basaran R, Uslu AA, Bezgin SU, Ogreden S, Yigit O.   +6 more
europepmc   +1 more source

Model-based design of subthalamic nucleus neurons using hybrid optimization. [PDF]

J Neurophysiol
Chen H, McIntyre CC.
europepmc   +1 more source

Beyond the brake: The subthalamic nucleus predominantly facilitates action in non-human primates. [PDF]

Prog Neurobiol
Yoshida A, Krauzlis RJ, Hikosaka O.
europepmc   +1 more source

Varying patterns of association between cortical large-scale networks and subthalamic nucleus activity in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Kohl O, Gohil C, Sure M, Schnitzler A, Florin E.   +4 more
europepmc   +1 more source

Increased beta-HFO phase-amplitude coupling in the subthalamic nucleus during movement in Parkinson's disease. [PDF]

Neuroimage Rep
Puszta A, Zádori D, Klivényi P.
europepmc   +1 more source