Results 91 to 100 of about 335,108 (249)

Staged Bilateral Magnetic Resonance‐Guided Focused Ultrasound for Treating Essential Tremor: Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Unilateral magnetic resonance guided focused ultrasound (MRgFUS) thalamotomy reduces tremor in essential tremor, yet disability often persists on the untreated side. The added benefit and safety of a staged contralateral lesion remain uncertain.
Nima Norbu Sherpa, Andrea Gonzalez Lezana, Gabriela Prilip, Kenji Fukutome, Nathan J. Pertsch, Ruth Reeve, Nadège Bault, Elsa Fouragnan   +7 more
wiley   +1 more source

Subthalamic projection to nucleus tegmenti pedunculopontinus in the rat

, 1981
A projection from the subthalamic nucleus to the nucleus tegmenti pedunculopontinus has been demonstrated in the rat using retrograde and anterograde transport of horseradish peroxidase.
Crossman, A. R., Jackson, A.
core   +1 more source

Molecular glucose imaging reveals functional brain reconfiguration by subthalamic deep brain stimulation in Parkinsonian rats

Translational Neurodegeneration
Background In order to elucidate the neuromodulatory mechanisms underlying therapeutic subthalamic deep brain stimulation (DBS), we here reverse-translate a methodological pipeline that integrates neurostimulation effect parameterization and molecular ...
Jiazhi Chen, Ningfei Li, Muthuraman Muthuraman, Nengxing Liang, Jens Volkmann, Takahiro Higuchi, Chi Wang Ip   +6 more
doaj   +1 more source

Focused stimulation of dorsal subthalamic nucleus improves reactive inhibitory control of action impulses [PDF]

, 2017
Frontal-basal ganglia circuitry dysfunction caused by Parkinson's disease impairs important executive cognitive processes, such as the ability to inhibit impulsive action tendencies.
Pallavaram, S., M.S. Okun, van den Wildenberg, W.P.M., K.E. Kanoff, P.F. D’Haese, D'Haese, P.F., D. Martinez-Ramirez, S.A. Wylie, Kanoff, K.E., Phibbs, F.T., van Wouwe, N.C., Martinez-Ramirez, D., Okun, M.S., B.M. Dawant, S. Pallavaram, J.S. Neimat, W.P.M. van den Wildenberg, Dawant, B.M., F.T. Phibbs, Neimat, J.S., N.C. van Wouwe, Wylie, S.A.   +21 more
core   +2 more sources

Effects of aging on nitrergic neurons in human striatum and subthalamic nucleus

Arquivos de Neuro-Psiquiatria, 2015
Nitric oxide (NO) is a major neurotransmitter associated with motor control in basal ganglia. Movement disorders, as essential tremor and Parkinson’s disease, are more prevalent on aged individuals.
Bruno Lopes dos Santos-Lobato, Elaine Aparecida Del-Bel, José Eymard Homem Pittella, Vitor Tumas   +3 more
doaj   +1 more source

Gray Matter Microstructure Measured Using Diffusion Imaging as a Biomarker of Severity in Lewy Body Diseases

Movement Disorders, EarlyView.
Abstract Background Despite widespread cortical involvement in Lewy body diseases, conventional gray matter magnetic resonance imaging (MRI) shows limited sensitivity. Diffusion‐weighted MRI‐derived microstructural measures have shown utility in Alzheimer's disease, but their application across the Lewy body disease spectrum remains limited ...
Angeliki Zarkali, Ivelina Dobreva, Naomi Hannaway, Rohan Bhome, George E.C. Thomas, Steffani Carrera, Amanda J. Heslegrave, Elena Veleva, Henrik Zetterberg, Rimona S. Weil   +9 more
wiley   +1 more source

Framework for Approaching Patients with Suboptimal Deep Brain Stimulation Therapy Response despite Stimulation Optimization

Movement Disorders Clinical Practice, EarlyView.
Pratik Talati, Meredith Spindler, Casey H. Halpern   +2 more
wiley   +1 more source

Voice and Speech in Deep Brain Stimulation in Dystonia: A Retrospective Study, Systematic Review, and Meta‐Analysis

Movement Disorders, EarlyView.
Abstract Background Relatively little is known about voice and speech abnormalities and their changes after deep brain stimulation (DBS) in patients with dystonia. Objective The aim was to determine the incidence of speech abnormalities, including laryngeal dystonia, among patients with dystonia receiving DBS and to characterize their response to this ...
Ian O. Bledsoe, Nutan Sharma, Marta San Luciano, Jill L. Ostrem, Nicole E. Buie, Gaia Arno, Mikayla Day, Kristina Simonyan   +7 more
wiley   +1 more source

Functional MRI with active, fully implanted, deep brain stimulation systems: Safety and experimental confounds [PDF]

, 2007
We investigated safety issues and potential experimental confounds when performing functional magnetic resonance imaging (fMRI) investigations in human subjects with fully implanted, active, deep brain stimulation (DBS) systems.
Lemieux, L., Thornton, John, Yousry, Tarek, Thobois, S., Pinto, Serge, Allen, P.J., Lemieux, Louis, Carmichael, David, Limousin-Dowsey, Patricia, Pinto, S., Limousin-Dowsey, P., Thornton, J.S., Thobois, Stéphane, Carmichael, D.W., Yousry, T., Allen, Philip   +15 more
core  

Quantifying local field potential dynamics with amplitude and frequency stability between ON and OFF medication and stimulation in Parkinson's disease

Neurobiology of Disease
Neural oscillations are critical to understanding the synchronisation of neural activities and their relevance to neurological disorders. For instance, the amplitude of beta oscillations in the subthalamic nucleus has gained extensive attention, as it ...
Xuanjun Guo, Shenghong He, Xinyi Geng, Pan Yao, Christoph Wiest, Yingnan Nie, Huiling Tan, Shouyan Wang   +7 more
doaj   +1 more source