Results 81 to 90 of about 351,721 (248)

The human subthalamic nucleus – knowledge for the understanding of Parkinson’s disease [PDF]

, 2010
The human subthalamic nucleus differs from those of experimental animals, especially rat. In this overview cytological, developmental, and connective discrepancies are enumerated.
T. Heida, Marani, Enrico, E. Marani, Heida, Tjitske; id_orcid   +3 more
core   +1 more source

Indirect Targeting of Subthalamic Deep Brain Stimulation Guided by Stereotactic Computed Tomography and Microelectrode Recordings in Patients With Parkinson’s Disease

Frontiers in Human Neuroscience, 2018
Objective: Magnetic resonance imaging fusion techniques guided by frame-based stereotactic computed tomography and microelectrode recordings are widely used to target the subthalamic nucleus. However, MRI is not always available.
Po-Hsun Tu, Zhuo-Hao Liu, Chiung Chu Chen, Chiung Chu Chen, Wey Yil Lin, Wey Yil Lin, Wey Yil Lin, Amy L. Bowes, Chin Song Lu, Chin Song Lu, Shih-Tseng Lee   +10 more
doaj   +1 more source

7 T MRI Connectivity‐Guided Reprogramming Improves Deep Brain Stimulation Motor Outcome in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an established treatment for Parkinson's disease (PD). Using 7‐Tesla (7 T) MRI connectivity analysis to visualize the patient‐specific STN motor subdivision, we hypothesize that reprogramming patients who are stimulated outside of this subdivision can improve their ...
Yarit Wiggerts, Annabel van der Weide, Rick Schuurman, Pepijn van den Munckhof, Rob MA de Bie, Martijn Beudel, Maarten Bot   +6 more
wiley   +1 more source

Subthalamic nucleus efferent projection to the cerebral cortex

, 1981
A direct projection from the subthalamic nucleus to the dorsal cerebral cortex has been demonstrated in the rat using a retrograde axonal transport technique.
Crossman, A. R., Jackson, A.
core   +1 more source

Subthalamic nucleus high-frequency stimulation restores altered electrophysiological properties of cortical neurons in parkinsonian rat. [PDF]

PLoS ONE, 2013
Electrophysiological recordings performed in parkinsonian patients and animal models have confirmed the occurrence of alterations in firing rate and pattern of basal ganglia neurons, but the outcome of these changes in thalamo-cortical networks remains ...
Bertrand Degos, Jean-Michel Deniau, Mario Chavez, Nicolas Maurice   +3 more
doaj   +1 more source

Anatomical and electrophysiological studies on the reciprocal projections between the subthalamic nucleus and nucleus tegmenti pedunculopontinus in the rat

, 1983
Reciprocal projections between the subthalamic nucleus of the diencephalon and the brain stem nucleus tegmenti pedunculopontinus have been demonstrated and studied anatomically and electrophysiologically in the rat. Injections of the fluorescent compound
Crossman, A. R., Rouzaire-Dubois, B., Féger, J., Jackson, A., Hammond, C.   +4 more
core   +1 more source

Subthalamic nucleus deep brain stimulation for Parkinson’s disease: Evidence for effectiveness and limitations from 12 years’ experience [PDF]

, 2014
Objective: To present the result and experience of subthalamic nucleus deep brain stimulation for Parkinson’s disease ...
Wong, Edith, Lau, Christine, Yeung, Jonas H.M., Chan, Danny T.M., Lau, Claire K.Y., Wong, Adrian, Ip, Vincent H.L., Chan, Anne Y.Y., Zhu, X. L., Kuo, S. H., Wong, Rosanna K.M., Mok, Vincent C.T., Tang, Venus, Poon, W. S.   +13 more
core   +1 more source

Morphological changes of glutamatergic synapses in animal models of Parkinson’s disease

Frontiers in Neuroanatomy, 2015
The striatum and the subthalamic nucleus are the main entry doors for extrinsic inputs to reach the basal ganglia circuitry. The cerebral cortex, thalamus and brainstem are the key sources of glutamatergic inputs to these nuclei.
Rosa M Villalba, Rosa M Villalba, Abraham eMathai, Abraham eMathai, Yoland eSmith, Yoland eSmith, Yoland eSmith   +6 more
doaj   +1 more source

Phase matters: A role for the subthalamic network during gait. [PDF]

PLoS ONE, 2018
The role of the subthalamic nucleus in human locomotion is unclear although relevant, given the troublesome management of gait disturbances with subthalamic deep brain stimulation in patients with Parkinson's disease.
Gabriele Arnulfo, Nicolò Gabriele Pozzi, Chiara Palmisano, Alice Leporini, Andrea Canessa, Joachim Brumberg, Gianni Pezzoli, Cordula Matthies, Jens Volkmann, Ioannis Ugo Isaias   +9 more
doaj   +1 more source

Use of the PROMIS and Neuro‐QoL to Evaluate Health‐Related Quality of Life following Unilateral Subthalamic Deep Brain Stimulation for Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Subthalamic nucleus deep brain stimulation (STN DBS) improves Parkinson's disease (PD)‐related motor symptoms, but how STN DBS impacts various aspects of patient‐perceived health‐related quality of life (HRQoL) is less clear. The Patient‐Reported Outcome Measurement Instrument (PROMIS) and Quality of Life in Neurological Disorders ...
Sarah A. Brinkerhoff, Frank Robinson, Roy C. Martin, Sandra Morales, Christopher L. Gonzalez, Christopher P. Hurt, Melissa Wade, Gary Cutter, Gitendra Uswatte, Harrison C. Walker, Victor A. Del Bene   +10 more
wiley   +1 more source