Results 81 to 90 of about 17,967 (218)

Socio‐Occupational Functioning after Subthalamic Deep Brain Stimulation in Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Socio‐occupational functioning in patients with Parkinson's disease (PD) treated with subthalamic nucleus deep brain stimulation (STN‐DBS) is not fully captured by standard motor and quality‐of‐life scales. Objectives To characterize patient‐reported socio‐occupational functioning after STN‐DBS and explore associated clinical and ...
Gabriele Imbalzano   +7 more
wiley   +1 more source

7 T MRI Connectivity‐Guided Reprogramming Improves Deep Brain Stimulation Motor Outcome in Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an established treatment for Parkinson's disease (PD). Using 7‐Tesla (7 T) MRI connectivity analysis to visualize the patient‐specific STN motor subdivision, we hypothesize that reprogramming patients who are stimulated outside of this subdivision can improve their ...
Yarit Wiggerts   +6 more
wiley   +1 more source

Hardware Sophistications in Subthalamic Nucleus Deep Brain Stimulation for Parkinson's Disease; Is the Juice Worth the Squeeze?

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background New sophisticated deep brain stimulation (DBS) systems enabling steering of current and aiming at improving further motor outcome and decreasing side effects have virtually replaced old omnidirectional systems, despite being more labor‐intensive and expensive.
Marwan Hariz, Patric Blomstedt
wiley   +1 more source

Early Experiences with Robotic-assisted Implantation of Deep Brain Stimulation Electrodes in Awake or Asleep Patients in Japan

open access: yesNeurologia Medico-Chirurgica
This study evaluated 14 patients who underwent robot-assisted deep brain stimulation electrode implantation and described our early experiences and workflows in both awake and asleep states.
Masafumi FUKUDA   +4 more
doaj   +1 more source

Automating Subthalamic Deep Brain Stimulation Programming with Evoked Resonant Neural Activity in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Optimal outcomes from subthalamic nucleus deep brain stimulation (STN‐DBS) for Parkinson's disease (PD) depend on accurate stimulation of an ideal functional target within the dorsolateral STN. Clinical programming is heuristic, and objective methods are needed to improve efficiency and consistency.
Kanae J. Nagao   +9 more
wiley   +1 more source

Temporal Interference Stimulation Modulates Resting State Functional Connectivity of Motor Circuit in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Transcranial temporal interference stimulation (TIs) targeting the subthalamic nucleus (STN) is a novel noninvasive neuromodulation approach with potential to improve motor symptoms in Parkinson's disease (PD). However, its underlying neuroimaging mechanisms remain unclear.
Yongxin Xu   +19 more
wiley   +1 more source

Abrupt Reoccurrence of Acquired Postencephalitic Hemidystonia After Unexpected Discontinuation of Thalamic DBS: An Embarrassing Situation

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Arif Abdulbaki   +3 more
wiley   +1 more source

Speech and Deep Brain Stimulation in Parkinson's Disease, Essential Tremor, and Dystonia: A Systematic Review and Meta‐analysis

open access: yesMovement Disorders, EarlyView.
Abstract Deep brain stimulation (DBS) effectively treats motor symptoms in movement disorders but often compromises speech through incompletely defined mechanisms. We conducted a PROSPERO‐registered systematic review and meta‐analysis of publications through August 2024 (CRD42024527738).
Elina Tripoliti   +15 more
wiley   +1 more source

Dopamine Agonists Rather than Deep Brain Stimulation Cause Reflection Impulsivity in Parkinson's Disease

open access: yesJournal of Parkinson’s Disease, 2013
Background: Dopamine agonist therapy is the main risk factor for impulse control disorders in Parkinson's disease (PD). However, it is unclear whether bilateral deep brain stimulation of the subthalamic nucleus also causes impairment in decision making ...
Atbin Djamshidian   +8 more
doaj   +1 more source

Synaptic release of dopamine in the subthalamic nucleus

open access: yesEuropean Journal of Neuroscience, 2004
AbstractThe direct modulation of subthalamic nucleus (STN) neurons by dopamine (DA) neurons of the substantia nigra (SN) is controversial owing to the thick caliber and low density of DA axons in the STN. The abnormal activity of the STN in Parkinson's disease (PD), which is central to the appearance of symptoms, is therefore thought to result from the
Cragg, S   +4 more
openaire   +2 more sources

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