Results 71 to 80 of about 351,721 (248)
Trials, 2011 Background Severe gait disturbances in idiopathic Parkinson's disease (PD) are observed in up to 80% of all patients in advanced disease stages with important impact on quality of life.
Fritz Melanie +7 more
doaj +1 more source
Epilepsia, EarlyView.Abstract Objective Although the centromedian nucleus of the thalamus (CM) is an increasingly considered deep brain stimulation (DBS) target for drug‐resistant epilepsy (DRE), there is significant variability in programming practices, which may contribute to heterogenous outcomes.
Mohammed A. AlQahtani +7 more
wiley +1 more source
Effect of Subthalamic Nucleus Stimulation on Pedunculopontine Nucleus Neural Activity
, 2016 Background: The pedunculopontine nucleus has recently been proposed as an alternative target for deep brain stimulation for the treatment of medically intractable Parkinson's disease.
Burchiel, K.J. +5 more
core +1 more source
The subthalamic nucleus, part II [PDF]
, 2008 Part II starts with a systemic model of the basal ganglia to evaluate the position of the STN in the direct, indirect and hyperdirect pathways.
Marani, Enrico +2 more
core +1 more source
Transcriptional Profile of the Developing Subthalamic Nucleus
eneuro, 2022 AbstractThe subthalamic nucleus (STN) is a small, excitatory nucleus that regulates the output of basal ganglia motor circuits. The functions of the STN and its role in the pathophysiology of Parkinson’s disease are now well established. However, some basic characteristics like the developmental origin and molecular phenotype of neuronal subpopulations
Ema Bokulić +2 more
openaire +4 more sources
Absence seizures: Update on signaling mechanisms and networks
Epilepsia Open, EarlyView.Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Brain networks modulated by subthalamic nucleus deep brain stimulation [PDF]
, 2021 The use of subthalamic nucleus deep brain stimulation in Parkinson's disease is limited in some patients by behavioural side-effects. Using perioperative electrophysiological recordings and presurgical neuroimaging, Accolla et al.
Horn, Andreas +6 more
core
Epilepsy surgery: From bench to the clinics
Epilepsia Open, EarlyView.Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley +1 more source
Parkinson's Disease, 2020 Background. Treatment of freezing of gait (FOG) is always challenging because of its unpredictable nature and multifactorial physiopathology. Intestinal levodopa infusion has been proposed in recent years as a valuable option for its improvement.
Belén González-Herrero +4 more
doaj +1 more source
The basal ganglia and the epilepsies
Epilepsia Open, EarlyView.Abstract The basal ganglia are an evolutionarily conserved neural circuit best known for the selection and sequencing of voluntary movement. Increasing evidence, however, indicates that these structures also play an important role in regulating pathological brain states, including seizures.
Willian Lazarini‐Lopes +2 more
wiley +1 more source