Results 121 to 130 of about 351,721 (248)

Remote Versus In‐Person Follow‐up Programming After Subthalamic Deep Brain Stimulation for Parkinson's Disease: A Multicenter Randomized Noninferiority Trial

Movement Disorders, EarlyView.
Abstract Background Remote programming of deep brain stimulation may improve access to specialized postoperative care for people with Parkinson's disease, but prospective randomized evidence remains limited. Objective We aimed to determine whether remote follow‐up programming after standardized inpatient initiation is noninferior to conventional in ...
Juhi Shaik, Weidong Zhang, Verena Zentsch, Carsten Buhmann, Ute Hidding, Thomas M. Kinfe, Martin Regensburger, Jost‐Julian Rumpf, Alfons Schnitzler, Jing Dong, Maximilian Scherer, Elisabeth Kaufmann, Johannes Levin, Alexander Crispin, Günter Höglinger, Jan H. Mehrkens, Thomas Koeglsperger   +16 more
wiley   +1 more source

Suppression of beta oscillations in the subthalamic nucleus following cortical stimulation in humans. [PDF]

, 2008
It is unclear how subthalamic nucleus activity is modulated by the cerebral cortex. Here we investigate the effect of transcranial magnetic stimulation (TMS) of the cortex on oscillatory subthalamic local field potential activity in the 8-35 Hz (alpha ...
Limousin, P, Eusebio, A, Insola, A, Tisch, S ; https://orcid.org/, Androulidakis, AG, Di Lazzaro, V, Pogosyan, A, Mazzone, P, Litvak, V, Doyle Gaynor, LMF, Brown, P, Kühn, AA, Dileone, M   +12 more
core   +1 more source

Synaptic release of dopamine in the subthalamic nucleus

European Journal of Neuroscience, 2004
AbstractThe direct modulation of subthalamic nucleus (STN) neurons by dopamine (DA) neurons of the substantia nigra (SN) is controversial owing to the thick caliber and low density of DA axons in the STN. The abnormal activity of the STN in Parkinson's disease (PD), which is central to the appearance of symptoms, is therefore thought to result from the
Cragg, S, Baufreton, J, Xue, Y, Bolam, J, Bevan, MD   +4 more
openaire   +2 more sources

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) C.M. de Lange   +26 more
wiley   +1 more source

Kinesthetic cells within the subthalamic nucleus and Deep Brain Stimulation for Parkinson's Disease

, 2020
We sought to determine the location of kinesthetic cell clusters within the subthalamic nucleus (STN) on magnetic resonance imaging, adjusted for ...
Pal, Gian, Bolier, Erik, Bot, Maarten, Metman, Leo Verhagen, Verhagen Metman, Leo, Stebbins, Glenn T., van den Munckhof, Pepijn, Sani, Sepehr   +7 more
core   +1 more source

Dopamine Agonists Rather than Deep Brain Stimulation Cause Reflection Impulsivity in Parkinson's Disease

Journal of Parkinson’s Disease, 2013
Background: Dopamine agonist therapy is the main risk factor for impulse control disorders in Parkinson's disease (PD). However, it is unclear whether bilateral deep brain stimulation of the subthalamic nucleus also causes impairment in decision making ...
Atbin Djamshidian, Sean S. O'Sullivan, Thomas Foltynie, Iciar Aviles-Olmos, Patricia Limousin, Alastair Noyce, Ludvic Zrinzo, Andrew J. Lees, Bruno B. Averbeck   +8 more
doaj   +1 more source

Intervention outcomes of children with non‐degenerative dystonia and associated hyperkinetic movement disorders: A scoping review

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify the outcomes reported in published studies of intervention approaches used with non‐degenerative childhood hyperkinetic movement disorders, including dystonia, dyskinesia, hypertonia, athetosis, chorea, cerebral palsy, involuntary movement, and kernicterus, and map them to the International Classification of Functioning ...
Hortensia Gimeno, Hannah Scott, Rocio Muñoz Sanchez, Alice Doohan, Deepti Chugh, Adrienne Harvey, Kirsty Stewart, Peter Rosenbaum, Grace Stynes, Khamani Edwards, Katherine Knighting   +10 more
wiley   +1 more source

Deep brain stimulation outcomes and management of childhood‐onset dystonia and associated hyperkinetic movements disorders

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To examine longitudinal changes in self‐selected goals and dystonia severity over 1 year, 2 years, and 5 years after deep brain stimulation (DBS) in children and young people (CYP) with dystonia and other hyperkinetic movement disorders, using CYP and caregiver reports.
Sinead Barkey, Laura Ainaga, Eva Maria Navarrete Muñoz, Verity McClelland, Keyoumars Ashkan, Richard Selway, Harutomo Hasegawa, Daniel E Lumsden, Jean‐Pierre Lin, Hortensia Gimeno   +9 more
wiley   +1 more source

Dopamine regulates the impact of the cerebral cortex on the subthalamic nucleus-globus pallidus network.

, 2001
The subthalamic nucleus-globus pallidus network plays a central role in basal ganglia function and dysfunction. To determine whether the relationship between activity in this network and the principal afferent of the basal ganglia, the cortex, is altered
Bolam, JP, Bevan, MD, Magill, Peter, P.J Magill, M.D Bevan, J.P Bolam   +5 more
core   +1 more source

Dopamine amplifies subthalamic long-latency responses to cortical stimulation in patients with Parkinson’s disease

npj Parkinson's Disease
The cortico-subthalamic hyperdirect pathway provides a rapid route for cortical influence over basal ganglia processing and is a key target of deep brain stimulation (DBS) in Parkinson’s disease (PD).
Jean-Christin Beyer, Alessia Cavallo, Jojo Vanhoecke, Richard M. Köhler, Bassam Al-Fatly, Gerd-Helge Schneider, Katharina Faust, Gregor A. Brandt, Andrea A. Kühn, Wolf-Julian Neumann   +9 more
doaj   +1 more source