Subthalamic stimulation causally modulates human voluntary decision-making to stay or go
npj Parkinson's DiseaseThe voluntary nature of decision-making is fundamental to human behavior. The subthalamic nucleus is important in reactive decision-making, but its role in voluntary decision-making remains unclear.
Yichen Wang +8 more
doaj +1 more source
Activation of Metabotropic Glutamate Receptor 5 Has Direct Excitatory Effects and Potentiates NMDA Receptor Currents in Neurons of the Subthalamic Nucleus [PDF]
, 2000 Hazar Awad +4 more
openalex +1 more source
Movement Disorders, EarlyView.Abstract Background Magnetic resonance‐guided focused ultrasound (MRgFUS) is an established surgical treatment for essential tremor, providing tremor relief without the need for an incision or general anesthesia. Meta‐analyses have been limited in their exploration of the durability of the treatment effect.
Alyssa Shiramba +8 more
wiley +1 more source
An FFT-based Synchronization Approach to Recognize Human Behaviors using STN-LFP Signal [PDF]
arXiv, 2016 Classification of human behavior is key to developing closed-loop Deep Brain Stimulation (DBS) systems, which may be able to decrease the power consumption and side effects of the existing systems. Recent studies have shown that the Local Field Potential (LFP) signals from both Subthalamic Nuclei (STN) of the brain can be used to recognize human ...
arxiv
Identification of the Anterior Nucleus of the Ansa Lenticularis in Birds as the Homolog of the Mammalian Subthalamic Nucleus [PDF]
, 2000 Yun Jiao +5 more
openalex +1 more source
Movement Disorders, EarlyView.Abstract Background Individual variability in clinical response to dopamine replacement therapy (DRT) is a key barrier to efficacious treatment for patients with Parkinson's disease (PD). A better understanding of the neurobiological sources of such interindividual differences is necessary to personalize DRT prescribing, inform future clinical ...
Alex I. Wiesman +5 more
wiley +1 more source
Developing vocal system impaired patient-aimed voice quality assessment approach using ASR representation-included multiple features [PDF]
arXivThe potential of deep learning in clinical speech processing is immense, yet the hurdles of limited and imbalanced clinical data samples loom large. This article addresses these challenges by showcasing the utilization of automatic speech recognition and self-supervised learning representations, pre-trained on extensive datasets of normal speech.
arxiv
Implication of the Subthalamic Nucleus in the Pathophysiology and Pathogenesis of Parkinson's Disease [PDF]
, 2000 Abdelhamid Benazzouz +5 more
openalex +1 more source
Movement Disorders, EarlyView.Abstract Background Deep brain stimulation (DBS) elicits oscillatory local field potentials in patients with Parkinson's disease (PD) and other movement disorders. Greater knowledge about the fast dynamics of these neural responses could shed light on circuit pathophysiology and inform novel approaches to neuromodulation therapies.
Sarah Brinkerhoff +7 more
wiley +1 more source
A Case Report of Bilateral Subthalamic Hemorrhages
Türk Nöroloji Dergisi, 2010 Spontaneous bilateral intracerebral hemorrhages are extremely rare. To further characterize this rare event, we report a 60-year-old man with chronic hypertension, who presented with bilateral subthalamic hemorrhages that consequently resulted in ...
Ayşe Oytun Bayrak
doaj +2 more sources