Results 171 to 180 of about 17,967 (218)

Subthalamic Nucleus

2015
Fue en 1865 cuando Jules Bernard Luys, un neurólogo francés, describió por primera vez una estructura gris de forma biconvexa, ubicada bilateralmente en la unión diencéfalo-mesencefálica y con una participación esencial en el control de los movimientos, a la que luego se le asignaron funciones adicionales en los procesos límbicos y cognitivos.
Fabián Piedimonte, Tania Acosta
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GABAergic control of the subthalamic nucleus

2007
The glutamatergic subthalamic nucleus (STN) is a key component of the basal ganglia, a group of subcortical brain nuclei important for voluntary movement and the site of dysfunction in Parkinson's disease. The rate and pattern of STN activity is precisely regulated by the reciprocally connected GABAergic external globus pallidus (GP(e)) and ...
Mark D, Bevan, Nicholas E, Hallworth, Jérôme, Baufreton   +2 more
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Subthalamic nucleus stimulation in Parkinson’s disease

Neurological Sciences, 2008
Deep brain stimulation (DBS) is an effective surgical treatment for advanced Parkinson's disease (PD), with significant advantages in morbidity-mortality and quality of life when compared to lesion techniques such as thalamotomy and/or pallidotomy. The procedure is indicated in patients with severe resting tremor, unresponsive to conventional medical ...
Marconi, Roberto, Landi, Andrea, Valzania, Franco   +2 more
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Dyskinesias and the subthalamic nucleus.

Annals of neurology, 2000
Severe dyskinesias or ballism can occur following hemorrhagic events in the subthalamic nucleus (STN), and it has recently been established that the STN plays a major role in the pathophysiology of the motor dysfunction of Parkinson's disease (PD) and that STN inhibition improves parkinsonian dysfunction.
Benabid, A L, Benazzouz, A, Limousin, P, Koudsie, A, Krack, Paul, Piallat, B, Pollak, Pierre   +6 more
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GABAergic interneurons in human subthalamic nucleus

Movement Disorders, 2005
AbstractThe subthalamic nucleus (STN) is considered a homogeneous structure composed essentially of projection neurons that exert a profound glutamate‐mediated excitatory influence upon the main output structures of the basal ganglia. It is currently the most efficient target for deep brain stimulations designed to alleviate symptoms of Parkinson's ...
Julie-Christine, Lévesque, André, Parent   +1 more
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Neurophysiological Refinement of Subthalamic Nucleus Targeting

Neurosurgery, 2002
ABSTRACT OBJECTIVE Advances in image-guided stereotactic surgery, microelectrode recording techniques, and stimulation technology have been the driving forces behind a resurgence in the use of functional neurosurgery for the treatment of movement disorders.
Djordje, Sterio, Martin, Zonenshayn, Alon Y, Mogilner, Ali R, Rezai, Kiril, Kiprovski, Patrick J, Kelly, Aleksandar, Beric   +6 more
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The Subthalamic Nucleus

2016
The glutamatergic subthalamic nucleus (STN) is a key node in the cortico-basal ganglia-thalamo-cortical circuit. As a component of the hyperdirect and indirect pathways, the STN is important for constraining movement, thought, and emotion through synaptic excitation of GABAergic basal ganglia output neurons.
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The microanatomical environment of the subthalamic nucleus

Journal of Neurosurgery, 2007
✓High-frequency stimulation of the subthalamic nucleus (STN) is a widely performed method to treat advanced Parkinson disease. Due to the limitations of current imaging techniques, the 3D microanatomy of the STN and its surrounding structures in the mesencephalon are not well known.
Kim, Rijkers, Yasin, Temel, Veerle, Visser-Vandewalle, Linda, Vanormelingen, Marjan, Vandersteen, Peter, Adriaensens, Jan, Gelan, Emile A M, Beuls   +7 more
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Genetics of subthalamic nucleus in development and disease

Experimental Neurology, 2005
The subthalamic nucleus (STN) is a crucial node in the basal ganglia. Clinical success in targeting the STN for deep brain stimulation in Parkinson's disease patients has prompted increased interest in understanding STN biology. In this report, we discuss recent evidence for transcription factor mediated regulation of STN development.
Steven T, Philips, Roger L, Albin, Donna M, Martin   +2 more
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Roles of the subthalamic nucleus and subthalamic HCN channels in absence seizures

Journal of Neurophysiology, 2012
Absence seizures consist of a brief and sudden impairment of consciousness. They are characterized by bilaterally synchronized spike and wave discharges (SWDs), which reflect abnormal oscillations in the thalamocortical loops. Recent studies have suggested that the basal ganglia are involved in generation of the SWDs, but their roles are poorly ...
Daisuke, Kase, Tsuyoshi, Inoue, Keiji, Imoto   +2 more
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