Results 211 to 220 of about 38,228 (259)
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Subthalamic nucleus

NeuroReport, 1996
Several brain sites are important for seizure control, including the area tempestas, superior colliculus, thalamus and substantia nigra. These sites are especially sensitive to changes in GABAergic transmission achieved by localized infusions of GABAergic agents.
J, Velísková, L, Velsek, S L, Moshé
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The microcircuitry of primate subthalamic nucleus

Parkinsonism & Related Disorders, 2007
Single-cell labeling experiments in cynomolgus monkeys have revealed that the subthalamic nucleus (STN) harbors several subtypes of projection neurons, each endowed with a highly patterned set of axon collaterals. This organizational feature allows single STN neurons to act directly upon the two major output structures of the basal ganglia--the ...
Martin, Parent, André, Parent
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Histogenesis of the subthalamic nucleus

Neuroscience, 1987
Literature presents divergent hypotheses on the histogenesis of the subthalamic nucleus. The basal plate of the mesencephalon, the dorsal hypothalamus (or the longitudinal subthalamic zone) and an area closely related to the mammillary nucleus have all been proposed as the site of origin of the neurons of the subthalamic nucleus.
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Subthalamic Nucleus

2015
Fue en 1865 cuando Jules Bernard Luys, un neurólogo francés, describió por primera vez una estructura gris de forma biconvexa, ubicada bilateralmente en la unión diencéfalo-mesencefálica y con una participación esencial en el control de los movimientos, a la que luego se le asignaron funciones adicionales en los procesos límbicos y cognitivos.
Fabián Piedimonte, Tania Acosta
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GABAergic control of the subthalamic nucleus

2007
The glutamatergic subthalamic nucleus (STN) is a key component of the basal ganglia, a group of subcortical brain nuclei important for voluntary movement and the site of dysfunction in Parkinson's disease. The rate and pattern of STN activity is precisely regulated by the reciprocally connected GABAergic external globus pallidus (GP(e)) and ...
Mark D, Bevan   +2 more
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Subthalamic nucleus stimulation in Parkinson’s disease

Neurological Sciences, 2008
Deep brain stimulation (DBS) is an effective surgical treatment for advanced Parkinson's disease (PD), with significant advantages in morbidity-mortality and quality of life when compared to lesion techniques such as thalamotomy and/or pallidotomy. The procedure is indicated in patients with severe resting tremor, unresponsive to conventional medical ...
Marconi, Roberto   +2 more
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GABAergic interneurons in human subthalamic nucleus

Movement Disorders, 2005
AbstractThe subthalamic nucleus (STN) is considered a homogeneous structure composed essentially of projection neurons that exert a profound glutamate‐mediated excitatory influence upon the main output structures of the basal ganglia. It is currently the most efficient target for deep brain stimulations designed to alleviate symptoms of Parkinson's ...
Julie-Christine, Lévesque   +1 more
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Neurophysiological Refinement of Subthalamic Nucleus Targeting

Neurosurgery, 2002
ABSTRACT OBJECTIVE Advances in image-guided stereotactic surgery, microelectrode recording techniques, and stimulation technology have been the driving forces behind a resurgence in the use of functional neurosurgery for the treatment of movement disorders.
Djordje, Sterio   +6 more
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The microanatomical environment of the subthalamic nucleus

Journal of Neurosurgery, 2007
✓High-frequency stimulation of the subthalamic nucleus (STN) is a widely performed method to treat advanced Parkinson disease. Due to the limitations of current imaging techniques, the 3D microanatomy of the STN and its surrounding structures in the mesencephalon are not well known.
Kim, Rijkers   +7 more
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Genetics of subthalamic nucleus in development and disease

Experimental Neurology, 2005
The subthalamic nucleus (STN) is a crucial node in the basal ganglia. Clinical success in targeting the STN for deep brain stimulation in Parkinson's disease patients has prompted increased interest in understanding STN biology. In this report, we discuss recent evidence for transcription factor mediated regulation of STN development.
Steven T, Philips   +2 more
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