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Modelling Optogenetic Subthreshold Effects
2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019We develop a system-level approach to modelling optogenetic-neurons firing behaviour in in-vivo conditions. This approach contains three sub-modules: 1) a Mie/Rayleigh scattering mode of light penetration in tissue; 2) a classic likelihood Poisson spiking train model; 3) a 4-state model of the Channelrhodopsin-2 (ChR2) channel added to a CA3 neuron ...
Junwen Luo +2 more
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IEEE Transactions on Very Large Scale Integration (VLSI) Systems, 2013
In this brief, we introduce a novel low-power dual mode logic (DML) family, designed to operate in the subthreshold region. The proposed logic family can be switched between static and dynamic modes of operation according to system requirements. In static mode, the DML gates feature very low-power dissipation with moderate performance, while in dynamic
Asaf Kaizerman +2 more
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In this brief, we introduce a novel low-power dual mode logic (DML) family, designed to operate in the subthreshold region. The proposed logic family can be switched between static and dynamic modes of operation according to system requirements. In static mode, the DML gates feature very low-power dissipation with moderate performance, while in dynamic
Asaf Kaizerman +2 more
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Behavioral characteristics of subthreshold depression
Journal of Affective Disorders, 2014This study examines differences in behavioral characteristics among individuals who are not depressed and individuals with subthreshold depression, and depression.We conducted structured interviews with 111 undergraduate students, who also completed self-report scales. The participants were divided into a non-depression group, a subthreshold depression
Koki, Takagaki +12 more
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Jealousy and Subthreshold Psychopathology: A Serotonergic Link
Neuropsychobiology, 2003<i>Background:</i> A few studies suggest that different neurotransmitters may play a role in the expression of jealousy. Our study aimed to explore the serotonergic system by means of the specific binding of <sup>3</sup>H-paroxetine (<sup>3</sup>H-Par) to platelet membranes of healthy subjects with and without ...
Marazziti D +8 more
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Nanometer Device Scaling in Subthreshold Circuits
2007 44th ACM/IEEE Design Automation Conference, 2007Subthreshold circuit design is a strong candidate for use in future low power applications. It is not clear, however, that device scaling to 45 nm and beyond will be beneficial in subthreshold circuits. We investigate the implications of device scaling on subthreshold circuits and find that the slow scaling of gate oxide thickness leads to a 60 ...
Scott Hanson +3 more
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Energy Optimality and Variability in Subthreshold Design
ISLPED'06 Proceedings of the 2006 International Symposium on Low Power Electronics and Design, 2006Recent progress in the development of subthreshold circuit design techniques has created the opportunity for dramatic energy reductions in many applications. However, energy efficiency comes at the price of timing and energy variability due to process variations.
Scott Hanson +5 more
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Subthreshold detrusor instability
Neurourology and Urodynamics, 1985AbstractAt the present time there is a paucity of clinical information on subthreshold (less than 15 cm of water) detrusor instability. In this study of 334 women with stress and/or urge incontinence, it was calculated that subthreshold detrusor instability resulted in urinary incontinence in 10% and urgency and frequency in 85%.
B. L. R. A. Coolsaet +3 more
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1985
During electrophysiological studies in patients with recurrent ventricular tachycardia, we and others made the observation that critically timed extrastimuli within the refractory period may prolong ventricular refractoriness and thus lead to interruption of a tachycardia, even though the extrastimulus itself does not induce ventricular depolarization.
E.-R. von Leitner, Th. Linderer
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During electrophysiological studies in patients with recurrent ventricular tachycardia, we and others made the observation that critically timed extrastimuli within the refractory period may prolong ventricular refractoriness and thus lead to interruption of a tachycardia, even though the extrastimulus itself does not induce ventricular depolarization.
E.-R. von Leitner, Th. Linderer
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Is Subthreshold Ionization a Chaotic Phenomenon?
1987The dynamics of strongly perturbed quantum systems is discussed in this paper through the study of a simple model. Aiming at a clarification of the role of classical chaos in quantum mechanics, the mechanism of strong field subthreshold ionization is illustrated in different situations.
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