Results 221 to 230 of about 2,709,938 (252)

Brain Functional Alterations and Association with Cognition in People with Preclinical Subjective Cognitive Decline and Objective Subtle Cognitive Difficulties

Neuroscience, 2023
Subjective cognitive decline (SCD) and objective subtle cognitive difficulties (Obj-SCD) are considered the initial stages of aberrant cognition prior to mild cognitive impairment (MCI) due to Alzheimer's disease (AD). We aimed to determine the difference of brain function of SCD and Obj-SCD, furthermore, to figure out which one could be the marker of ...
Fengchun Hua
exaly   +4 more sources

Subtle Thyroid Dysfunction Is Not Associated with Cognitive Decline: Results from the ELSA-Brasil

Journal of Alzheimer's Disease, 2021
Background: Subtle thyroid alterations have a controversial role in cognition. Objective: We investigated the longitudinal association of baseline thyroid function, thyrotropin (TSH), and thyroxine (FT4) levels with cognitive performance after 4 years of follow-up in middle-aged and older adults without overt thyroid dysfunction. Methods: We included 4,
Claudia, Szlejf   +6 more
openaire   +2 more sources

Subtle cognitive impairment is associated with subtle instrumental activities of daily living defecits, but not severity of memory complaints in sucjective cognitive decline

Alzheimer's & Dementia, 2023
AbstractBackgroundSubjective cognitive decline (SCD) can be considered as the preclinical manifestation of Alzheimer’s disease. The objective of this study was to examine whether there would be differences of the clinical correlates due to evidence of subtle cognitive imparment (SCI) in inividuals with SCD.MethodOne‐hundred‐and‐fifty‐five individuals ...
Seon Young Ryu   +3 more
openaire   +1 more source

2 Cognitive Heterogeneity and Risk of Progression in Data-Driven Subtle Cognitive Decline Phenotypes

Journal of the International Neuropsychological Society, 2023
Objective:There is increasing recognition of cognitive and pathological heterogeneity in early-stage Alzheimer’s disease and other dementias. Data-driven approaches have demonstrated cognitive heterogeneity in those with mild cognitive impairment (MCI), but few studies have examined this heterogeneity and its association with progression to MCI ...
Kelsey R Thomas   +7 more
openaire   +1 more source

Meaningful cognitive decline is uncommon in virally suppressed HIV, but sustained impairment, subtle decline and abnormal cognitive aging are not

open access: yesEClinicalMedicine, 2023
Background High antiretroviral therapy (ART) coverage and viral suppression among people with HIV (PWH) in Australia provide a unique context to study individual cognitive trajectories, cognitive aging and factors associated with longitudinal cognitive ...
Andrew Carr   +2 more
exaly   +1 more source

Related amyloid burden and cortical atrophy in individuals with subtle cognitive decline

Alzheimer's & Dementia, 2023
AbstractBackgroundSubtle cognitive decline represents a stage of subclinical cognitive deterioration in which pathological biomarkers, particularly for Alzheimer’s disease may be present, including early cortical atrophy and amyloid deposition. Using individual items from the Montreal Cognitive Assessment (MoCA) and k‐modes cluster analysis, we ...
Tess E.K. Cersonsky, Leslie Ann D Brick
openaire   +1 more source

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