Results 61 to 70 of about 621,209 (319)

Inducing and Enhancing Antimicrobial Activity of Mining-Soil-Derived Actinomycetes Through Component Modification of Bennett’s Culture Medium

Microbiology Research
This study investigated the effect of different culture agar media, derived from Bennett’s medium, on the antimicrobial activity of 15 Streptomyces sp. and 1 Lentzea sp. strains isolated from mining environments. The media were prepared from the standard
Soumia Ait Assou, Jaouad Anissi, Laurent Dufossé, Mireille Fouillaud, Mohammed EL Hassouni   +4 more
doaj   +1 more source

Potential for Meaning Making in Mathematics Textbooks

Designs for Learning, 2019
A Multimodal Analysis of Subtraction in Swedish Year 1   Textbooks are a common teaching tool widely used in children’s mathematical education. Comparative studies of textbooks have focused on different aspects, such as content, mathematical symbols and ...
Malin Norberg
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Number processing and arithmetic skills in children with cochlear implants

Frontiers in Psychology, 2014
Though previous findings report that hearing impaired children exhibit impaired language and arithmetic skills, our current understanding of how hearing and the associated language impairments may influence the development of arithmetic skills is still ...
Silvia ePixner, Martin eLeyrer, Korbinian eMoeller   +2 more
doaj   +1 more source

Continuous-variable measurement-device-independent quantum key distribution with photon subtraction

, 2018
It has been found that non-Gaussian operations can be applied to increase and distill entanglement between Gaussian entangled states. We show the successful use of the non-Gaussian operation, in particular, photon subtraction operation, on the continuous-
Bai, Dong-Yun, Bao, Wan-Su, Huang, Peng, Ma, Hong-Xin, Wang, Shi-Yu, Zeng, Gui-Hua   +5 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Achieving arithmetic learning in honeybees and examining how individuals learn

Communicative & Integrative Biology, 2019
In recent years honeybees have demonstrated intriguing numerical capacities, leading to the recent discovery of their ability to perform simple arithmetic by learning to add or subtract ‘one’ using symbolic representations of operators.
Scarlett R. Howard, Aurore Avarguès-Weber, Jair E. Garcia, Andrew D. Greentree, Adrian G. Dyer   +4 more
doaj   +1 more source

Background subtraction and jet quenching on jet reconstruction

, 2012
In order to assess the ability of jet observables to constrain the characteristics of the medium produced in heavy-ion collisions at the LHC, we investigate the influence of background subtraction and jet quenching on jet reconstruction, with focus on ...
Aad, Abelev, Armesto, Cacciari, Chatrchyan, Chatrchyan, Kodolova, Letícia Cunqueiro, Liliana Apolinário, Néstor Armesto   +9 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source